VU University medical Center, Amsterdam (Netherlands) Head subdivision Gynaecology. Professor in Obstetrics and Gynaecology

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1 Curriculum vitae PERSONAL INFORMATION Judith Huirne WORK EXPERIENCE November 2007 Present Gynaecologist VU University medical Center, Amsterdam (Netherlands) Head subdivision Gynaecology April 2017 Present Professor in Obstetrics and Gynaecology VU University medical center, Amsterdam (Netherlands) April 2007 November 2007 Fellowship endoscopic surgery Ulleval University Hospital Oslo (Norway) EDUCATION AND TRAINING Training Obstetrics and Gynecology VU University medical centre, Amsterdam (Netherlands) PhD Department of Obstetrics and Gynecology, Vrije Universiteit medical centre (Netherlands) Dissertation: The optimal GnRH antagonist regimen to compare with GnRH agonists for use in IVF Training epidemiology EMGO (Netherlands), Amsterdam: epidemiological research (A010), principles of epidemiologic data-analyses (A020), linear regression and variance analyses (A030), Logistic regression and survival analyses (A050), epidemiology applications (A060) ADDITIONAL INFORMATION Expertise Special interest: minimal invasive surgery, benign gynaecology, fibroids, adenomyosis, niches. ehealth Publications International (peer reviewed) Peters MJ, Stinstra JG, Broek SP van den, Huirne JAF, Quartero HWP, Brake HJM ter, Rogalla H. On the fetal magnetocardiogram. Bioelec trochemistry and Bioenergetics 1998: 47; Janssens RMJ, Brus L, Cahill DJ, Huirne JA, Schoemaker J, Lambalk CB. Direct ovarian effects and safety aspects of GnRH agonists and antagonists. Human Reproduction Update 2000: 6; Huirne JA, Lambalk CB. Gonadotropin-releasing-hormone-receptor antagonists. Lancet 2001: 358; Loenen ACD van, Huirne JA, Schats R, Hompes P, Lambalk CB - GnRH agonists, antagonits, and assisted conception. Sem Reprod Med. 2002: 20; Huirne JA, Lambalk CB, Van Loenen ACD, Schats R, Hompes PGA, Fauser BCJM, Macklon NS. Contemporary pharmacological manipulation in assisted reproduction. Drugs 2004: 63; Van Montfrans JM, van Hooff MH, Huirne JA, Tanahatoe SJ, Sadrezadeh S, Martens F, van Vught JM, Lambalk CB. Basal FSH concentrations as a marker of ovarian ageing are not related to pregnancy outcome in a general population of women over 30 years. Hum Reprod 2004: 19; /3/18 European Union, Page 1 / 12

2 7. Huirne JA, van Loenen AC, Scharts R, McDonnell J, Hompes PG, Schoemaker J, Homburg R, Lambalk CB. Dose-finding study of daily gonadotropin-releasing hormone (GnRH) antagonist for the prevention of premature luteinizing hormone surges in IVF/ICSI: antide and hormone levels. Hum Reprod 2004: 19; Lambalk CB, Huirne JAF, Macklon NS, Fauser BCJM, Homburg R. Ovulation induction with clomiphene or gonadotropins. International congress series 2005:1279; Huirne JA, van Loenen AC, Scharts R, McDonnell J, Hompes PG, Schoemaker J, Homburg R, Lambalk CB. Dose-finding study of daily gonadotropin-releasing hormone (GnRH) antagonist for the prevention of premature luteinizing hormone surges in IVF/ICSI: Optimal changes in LH and progesterone levels for clinical pregnancy. Hum Reprod 2005: 20; Huirne JA, van Loenen AC, Donnez J, Pierer C, Homburg R, Schats R, McDonnell J, Lambalk CB. Effect of an oral contraceptive pill on follicular development in IVF/ICSI patients receiving a GnRH antagonist: a randomized study. RBM-online 2006: 13; Huirne JA, Hugues JN, Pirard C, Fischl F, Sage JC, Pouly JL, Obruca A, Braat DM, van Loenen AC, Lambalk CB. Cetrorelix in an oral contraceptive-pretreated stimulation cycle compared with buserelin in IVF/ICSI patients treated with rhfsh: a randomized, multicentre, phase IIIb study. Human Reproduction 2006: 21; Homburg R, Pap H, Brandes M, Huirne JA, Hompes P, Lambalk CB. Endometrial biopsy during induction of ovulation with clomiphene citrate in polycystic ovary syndrome. Gynecol Endocrinol. 2006: 22: Huirne JA, Homburg R, Lambalk CB. Are GnRH antagonists comparable to agonists for use in IVF? Human Reproduction 2007; 22: Brolmann HR, Huirne JAF. Current Treatment Options and Emerging Strategies for Fibroid Management. The Internet Journal of Gynecology and Obstetrics 2008; Volume 10, Number Huirne JA, Kennedy R, Stolzenberg J, Brölmann HAM. What is the impact of surgical expertise and how to get it? Gynaecological surgery : Brolmann HAM, Vonk-Noordgraaf A, Bruinvels D, de Vet HC, Dirksz A, Huirne JAF. Can prolonged sick leave after gynecological surgery be predicted? An observational study in the Netherlands. Surgical Endoscopy : Bij de Vaate AJM, Brolmann, HA, Van der Slikke JW, Emanual MH, Huirne JAF. Gel instillation sonohysterography (GIS) and saline contrast sonohysterography (SCSH): comparison of two diagnostic techniques. Ultrasound Obstet Gynecol : Bij de Vaate AJM, Brolmann HA, Schats R, Wouters MGAJ, Van der Slikke JW, Huirne JAF. Therapeutical options of caesarean scar pregnancy; case series and literature review. J Clin Ultrasound : Bij de Vaate AJ, Huirne JA, van der Slikke JH, Schats R, Brölmann HA. Medical treatment of caesarean scar pregnancy. J Minim Invasive Gynecol : Brölmann HA, Bijdevaate AJ, Vonk Noordegraaf A, Janssen PF, Huirne JA. Hysterectomy or a minimal invasive alternative? A systematic review on quality of life and satisfaction. Gynecol Surg Sep;7(3): Banga FR, Huirne JA, Korsen T, Homburg R, Hompes PG, Lambalk CB. Pituitary sensitizing effect of GnRH antagonists: a mechanism explaining LH escape during IVF? Hum Reprod : BijdeVaate AJ, Brölmann HA, van der Voet LF, van der Slikke JW, Veersema S, Huirne JA. Ultrasound evaluation of the caesarean scar: relation between a niche and postmenstrual spotting. Ultrasound Obstet Gynecol : Janssen PF, Brolmann HAM, Huirne JAF. Recommendations to prevent urinary tract injuries during laparoscopic hysterectomy: a systematic Delphi procedure among experts. J Minim Invasive Gynecol : Vonk Noordegraaf A, Huirne J, Brölmann H, van Mechelen W, Anema J. Multidisciplinary convalescence recommendations after gynaecological surgery: a modified Delphi method among experts. BJOG : Janssen P, Brölmann H, van Kesteren P, Bongers M, Thurkow A, Heymans M, Huirne J. Perioperative outcomes using LigaSure compared with conventional bipolar instruments in 24/3/18 European Union, Page 2 / 12

3 laparoscopic hysterectomy: a randomised controlled trial. BJOG : NB Burger, HAM Brolmann, JI Einarsson, A Langebrekke, JAF Huirne. Effectiveness of abdominal cerclage placed via laparotomy or laparoscopy: systematic review. J Minim Invasive Gynecol : Naji O, Abdallah Y, Bij de Vaate A, Smith A, Pexsters A, Stalder C, McIndoe A, Ghaem-Maghami S, Lees C, Brölmann HA, Huirne JA, Timmerman D, Bourne T. Standardized approach for imaging and measuring Cesarean section scars using ultrasonography. Ultrasound Obstet Gynecol Mar;39(3): Naji O, Abdallah Y, Bij de Vaate A, Smith A, Pexsters A, Stalder C, McIndoe A, Ghaem-Maghami S, Lees C, Brölmann HA, Huirne JA, Timmerman D, Bourne T. Standardized approach for imaging and measuring Cesarean section scars using ultrasonography. EDITORIAL COMMENT. Ultrasound Obstet Gynecol (7): A Vonk Noordegraaf, JAF Huirne, HAM Brölmann, MH Emanuel, PJM van Kesteren, G Kleiverda, JP Lips, A Mozes, A Thurkow, W van Mechelen and JR Anema. Effectiveness of a multidisciplinary care program on recovery and return to work of patients after gynaecological surgery; design of a randomized controlled trial. BMC Health Serv Res Feb 1;12(1): PJ van Empel, LB van Rijssen, JP Commandeur, MGE Verdam, JA Huirne, F Scheele, HJ Bonjer, WJ Meijerink. Validation of a new box trainer-related tracking device: the TrEndo. Surg Endosc. 2012;26: Janssen PF, Brölmann HA, van Kesteren PJ, Bongers MY, Thurkow AL, Heymans MW, Huirne JA. Perioperative outcomes using LigaSure compared to conventional bipolar instruments in laparoscopic salpingo-oophorectomy: a randomized controlled trial. Surg Endosc 2012;26: Janssen PF, Brölmann HA, Huirne JAF. Effectiveness of electrothermal bipolar vessel-sealing devices versus other electrothermal and ultrasonic devices for abdominal surgical hemostasis: a systematic review. Surg Endosc. 2012;26: PJ van Empel, M Strypet, JA Huirne, F Scheele, WJ Meijerink. Voluntary Autonomous Simulator Based Training in Minimally Invasive Surgery, Residents' Compliance and Reflection. J Surg Educ Jul;69(4): Vonk Noordegraaf A, Huirne JAF, Pittens CACM, Broerse JEW, Brölmann HAM, Mechelen W, Anema JR. E-health program to empower patients in returning to normal activities and work after gynaecological surgery: Intervention Mapping as a useful method for development. J Med Internet Res Oct 19;14(5):e Burger NB, Einarsson JI, Brölmann HAM, Vree FEM, McElrath TF, Huirne JAF Preconceptual laparoscopic abdominal cerclage: a multicenter cohort study. Am J Obstet Gynecol Oct;207(4):273.e1-12. Epub 2012 Jul Janssen PF, Brölmann HAM, Huirne JAF. Causes and Prevention of Laparoscopic Ureter Injuries: an Analysis of 31 Cases during Laparoscopic Hysterectomy in the Netherlands. Surg Endosc Mar;27(3): B. Torrenga, J.A. Huirne, J.H.T.M van Waesberghe, A.C. Bolte, J.I.P de Vries. Postpartum monitoring of retained placenta, two cases with placenta percreta. Acta Obstet Gynecol Scand Apr;92(4): van Empel PJ, Verdam MG, Huirne JA, Bonjer HJ, Meijerink WJ, Scheele F.PJ. Open knot-tying skills: residents skills assessed. J Obstet Gynaecol Res May;39(5): Burger NB, Brölmann HA, Huirne JA, Einarsson JI, McElrath TF, Vree FE. Reply on laparoscopic cerclage. Am J Obstet Gynecol Apr;208: van Empel PJ, Commandeur JP, van Rijssen LB, Verdam MG, Huirne JA, Scheele F, Bonjer HJ, Jeroen Meijerink W. Learning curve on the TrEndo laparoscopic simulator compared to an expert level. Surg Endosc Aug;27: Pittens CA, Vonk Noordegraaf A, Van Veen SC, Anema JR, Huirne JA, Broerse JE. The involvement of gynaecological patients in the development of a clinical guideline for resumption of (work) activities in the Netherlands. (accepted Health Expectations) The involvement of gynaecological patients in the development of a clinical guideline for resumption of (work) activities in the Netherlands. Health Expect Aug Verschoor MA, Lemmers M, Bossuyt PM, Graziosi GC, Hajenius PJ, Hendriks DJ, van Hooff MA, van Meurs HS, Opmeer BC, van Tulder MW, Bouwma L, Catshoek R, Geomini P, Klinkert ER, Langenveld J, Nieboer TE, van der Ploeg JM, Radder CM, Spinder T, van der Voet LF, Mol BW, Huirne JA, Ankum WM. Surgical versus expectant management in women with an incomplete 24/3/18 European Union, Page 3 / 12

4 evacuation of the uterus after treatment with misoprostol for miscarriage: the MisoREST trial BMC Pregnancy Childbirth May 2;13: Herman MC, van den Brink MJ, Geomini PM, van Meurs HS, Huirne JA, Eising HP, Timmermans A, Pijnenborg J, Klinkert ER, Coppus SF, Nieboer T, Catshoek R, van der Voet LF, van Eijndhoven HW, Graziosi G, Veersema BS, van Kesteren PJ, Langenveld J, Smeets NA, van Vliet HA, van der Steeg JW, Leeuwen YL, Dekker JH, Mol BW, Berger MY, Bongers MY. Levonorgestrel releasing intrauterine system (Mirena) versus endometrial ablation (Novasure) in women with heavy menstrual bleeding: a multicentre randomised controlled trial. BMC Womens Health Aug 8;13(1):32. [Epub ahead of print] 44. Bouwsma EV, Vonk Noordegraaf A, Szlávik Z, Brölmann HA, Emanuel MH, Lips JP, van Mechelen W, Mozes A, Thurkow AL, Huirne JA, Anema JR. Process Evaluation of a Multidisciplinary Care Program for Patients Undergoing Gynaecological Surgery. J Occup Rehabil Sep 22. [Epub ahead of print] 45. PJ van Empel, LB van Rijssen, JP Commandeur, MGE Verdam, JA Huirne, F Scheele, HJ Bonjer, WJ Meijerink Objective versus subjective assessment of laparoscopic skill, Minimally invasive surgery Vonk Noordegraaf A, Anema JR, Van Mechelen W, MW Heymans, Brölmann HAM, Huirne JAF. Prediction of return to work after gynaecological surgery; an prospective observational cohort study. BJOG 2014 Mar;121(4): Stoelinga B, Hehenkamp WJ, Brölmann HA, Huirne JA. The use of realtime elastosonography in the assessment of uterine disorders. Ultrasound Obstet Gynecol Feb;43(2): BijdeVaate AJ, van der Voet LF, Naji O, Witmer M, Veersema S, Brölmann HAM, Bourne T, Huirne JAF. The prevalence, potential risk factors for development and symptoms related to the presence of uterine niches following Caesarean section: a systematic review. Ultrasound Obstet Gynecol [Epub ahead of print aug 2013] 2014 Apr;43(4): Hooker AB, Thurkow A, Heymans MW, Scheele F, Brölmann H, Huirne JAF. Prevalence of intra uterine adhesions (IUA) post miscarriage: a systematic review and meta-analysis. Hum Reprod Update Mar-Apr;20(2): HAM Brölmann, BijdeVaate AJ, van der Voet LF, Naji O, Witmer M, Veersema S, Brölmann HAM, Bourne T, Huirne JAF. Cesarean scar defects: an under recognized cause of abnormal uterine bleeding and other gynecologic complications. The Journal of Minimally Invasive Gynecology 2013; 20: LF van der Voet, M BijdeVaate, S Veersema, HAM Brölmann, JAF Huirne. Long term complications of caesarean section, the niche in the scar: a prospective cohort study on niche prevalence and relation with abnormal uterine bleeding. BJOG Jan;121(2): LF van der Voet, AJ Vervoort, S Veersema, M BijdeVaate, HAM Brölmann, JAF Huirne. Minimally invasive therapy for gynecological symptoms related to a niche in the caesarean scar; a systematic review. BJOG Jan;121: Nieuwenhuis LL, BijdeVaate M, Hehenkamp WJK, Heymans MW, Brölmann HAM, Huirne JAF. Diagnostic and clinical value of 3D gel installation sonohysterography in addition to 2D gel installation sonohysterography in the assessment of intrauterine abnormalities. Eur J Obstet Gynecol Reprod Biol Jan 30. pii: S (14) doi: /j.ejogrb Vonk Noordegraaf A, Anema J, van Mechelen W, Knol D, van Baal W, van Kesteren P, Brölmann H, Huirne J. A personalised ehealth programme reduces the duration until return to work after gynaecological surgery: results of a multicentre randomised trial. BJOG Feb 11. doi: / [Epub ahead of print] 55. Nieuwenhuis LL, BijdeVaate M, Hehenkamp WJK, Heymans MW, Brölmann HAM, Huirne JAF. Reproducibility of three-dimensional gel instillation sonohysterography in the assessment and classification of intrauterine abnormalities. Eur J Obstet Gynecol Reprod Biol Aug;179: doi: /j.ejogrb Epub 2014 May LL Nieuwenhuis, HE Betjes, WJK Hehenkamp, MW Heymans, HAM Brolmann, JA Huirne. The identification of the most optimal 3D Power Doppler angiographic parameter with the highest interobserver agreement in the assessment of Uterine Leiomata. J Clin Ultrasound Aug 11. doi: /jcu [Epub ahead of print] 57. EVA Bouwsma, JR Anema, A VonkNoordegraaf, DL Knol, JE Bosmans, SE Schraffordt Koops, PJM van Kesteren, WM van Baal, JP Lips, MH Emanuel, P Scholten, A Mozes, AH Adriaanse, HAM Brölmann, JAF Huirne. Cost-effectiveness of a tailored, web-based care program to enhance postoperative recovery in gynecologic patients in comparison with usual care; research protocol of a 24/3/18 European Union, Page 4 / 12

5 stepped wedgecluster randomized trial. JMIR Res Protoc Jun 18;3(2):e Nieuwenhuis LL, Hermans FJR, Bij de Vaate AJM, Leeflang MMG, Brölmann HAM, Mol BWJ, Clark TJ, Huirne JAF. Three-dimensional saline infusion sonohysterography for the diagnosis of focal intracavitary lesions (Protocol). Cochrane Database of Systematic Reviews 2014, Issue 6. Art. No.: CD DOI: / CD Bij de Vaate AJ, van der Voet LF, Naji O, Witmer M, Veersema S, Brölmann HA, Bourne T, Huirne JA. Reply: Niche risk factor for uterine rupture? Ultrasound Obstet Gynecol Sep;44: MAC Verschoor; M Lemmers; MZ Wekker; JA Huirne; M Goddijn; BW Mol, WM Ankum. Practice variation in management of first trimester miscarriage in the Netherlands; a nationwide survey. Obstet Gynecol Int. 2014;2014: Epub 2014 Nov 4. PMID: Free PMC Article 61. Lemmers M, Verschoor MA, Hooker AB, Opmeer BC, Limpens J, Huirne JA, Ankum WM, BW Mol. Does curettage increase the risk of preterm birth in the subsequent pregnancy? A ystematic review and meta-analysis. Hum Reprod Jan;31: B.Stoelinga, JA Huirne, MW Heymans, JA Reekers, WM Ankum, WJ Hehenkamp. The estimation of the volume of the fibroid uterus: a comparison of ultrasound and bimanual examination versus volume at MRI or hysterectomy Eur J Obstet Gynecol Reprod Biol Jan;184C: Marjolein Bij de Vaate AJ, Linskens IH, van der Voet LF, Twisk JW, Brölmann HA, Huirne JA. Reproducibility of three-dimensional ultrasound for the measurement of a niche in a caesarean scar and assessment of its shape. J Obstet Gynecol Reprod Biol May;188: Bij de Vaate AJ, van der Voet LF, Naji O, Witmer M, Veersema S, Brölmann HA, Bourne T, Huirne JA. Reply: Niche risk factor for uterine rupture? Ultrasound Obstet Gynecol Sep;44(3): Nieuwenhuis LL, Betjes HE, Hehenkamp WJ, Heymans MW, Brolmann HA, Huirne JA. The use of 3D power Doppler ultrasound in the quantification of blood vessels in uterine fibroids: feasibility and reproducibility. J Clin Ultrasound Mar;43(3): AJM Vervoort, LB Uittenbogaard, W.Hehenkamp, HAM Brölmann, JA Huirne. Why do niches develop in uterine CS scars? Hypothesis on the aetiology. Hum Reprod : Vervoort AJ, Van der Voet LF, Witmer M, Thurkow AL, Radder CM, van Kesteren PJ, Quartero HW, Kuchenbecker WK, Bongers MY, Geomini PM, de Vleeschouwer LH, van Hooff MH, van Vliet HA, Veersema S, Renes WB, van Meurs HS, Bosmans J, Oude Rengerink K, Brölmann HA, Mol BW, Huirne JA. The HysNiche trial: hysteroscopic resection of uterine caesarean scar defect (niche) in patients with abnormal bleeding, a randomised controlled trial. BMC Womens Health Nov 12;15(1): AB. Hooker, H Aydin, HAM Brölmann, JAF Huirne. Long-term complications and reproductive outcome following medical and surgical management of retained products of conception (RPOC), a systematic review. Fertil Steril 2016;105: e2 69. Lemmers M, Verschoor MA, Hooker AB, Opmeer BC, Limpens J, Huirne JA, Ankum WM, Mol BW. Dilatation and curettage increases the risk of subsequent preterm birth: a systematic review and meta-analysis. Hum Reprod. 2016;31: DCR van Vliet, E van der Meij, EVA Bouwsma, A Vonk-Noordegraaf, B van den Heuvel, WJHJ Meijerink, WM van Baal, JAF Huirne, JR Anema. A modified Delphi method towards multidisciplinary consensus on convalescence recommendations after abdominal surgery. Surg Endosc Dec;30(12): Lemmers M, Verschoor MAC, Oude Rengerink K, Naaktgeboren C, Opmeer BC, Bossuyt PM, Huirne JAF, Janssen CAH, Radder C, Klinkert ER, Langenveld J, Catshoek R., Van der Voet L, Siemens F, Geomini P, Van Hooff MH, Ankum WM, Mol BWJ. MisoREST: Surgical versus expectant management in women with an incomplete evacuation of the uterus after misoprostol treatment for miscarriage: a randomised controlled trial. Hum Reprod. 2016;31: Hooker A, Fraenk D, Brölmann H, Huirne J. Prevalence of intrauterine adhesions after termination of pregnancy: a systematic review. Eur J Contracept Reprod Health Care Aug;21(4): doi: / E van der Meij, F. Schaafsma, J.Huirne, H.Anema. The effect of perioperative e-health interventions on the postoperative course: a systematic review of randomised and non-randomised controlled trials e-health interventions. PLoS One Jul 6;11(7):e doi: /journal.pone ecollection FA Groenman, C.Nikkels, M van Trotsenburg, J.Huirne, JW Trum. A new procedure: Robotassisted laparoscopic colpectomy in female-to-male transgender patients. Surg Endosc Nov /3/18 European Union, Page 5 / 12

6 [Epub ahead of print] 75. E van der Meij, JAF Huirne, EVA Bouwsma, JM van Dongen, CB Terwee, PM van de Ven, CM den Bakker, S van der Meij, WM van Baal, WKG Leclercq, PMAJ Geomini, ECJ Consten, SE Schraffordt Koops, PJM van Kesteren, HBAC Stockmann, D ten Cate, PHP Davids, PC Scholten, B van den Heuvel, FG Schaafsma, WJHJ Meijerink, HJ Bonjer, JR Anema. Substitution of usual perioperative care by e-health to enhance postoperative recovery in patients undergoing general surgical or gynecological procedures; study protocol of a randomized controlled trial. JMIR Res Protoc Dec 21;5(4):e C.C.J. Alleblas, M.A.G. Formanoy, R. Könemann, Huirne J.A., T.E. Nieboer Ergonomics in gynecologists daily practice: a nationwide survey in the Netherlands. Work. 2016;55(4): JA Kroese, M Velde, LP Morssink, MH Zafarmand, P Geomini, PJM van Kesteren, CM Radder, LF van der Voet, JPWR Roovers, GCM Graziosi, WM van Baal, J van Bavel, R Catshoek, ER Klinkert, JAF Huirne, TJ Clark, BWJ Mol, N Reesink-Peters. Word catheter and marsupialization in women with a cyst or abscess of the Bartholin gland: a randomised clinical trial. BJOG Jan;124(2): Nvan Hanegem, MC Breijer, SA Slockers, MH Zafarmand, PMAJ Geomini, R Catshoek, J MA Pijnenborg, LF van der Voet, PHLJ Dijkhuizen, GCR van Hoecke, N Reesink-Peters, S Veersema, MHA van Hooff, PJM van Kesteren, JA Huirne, BC Opmeer, MY Bongers, BWJ Mol, A Timmermans. Diagnostic work up for postmenopausal bleeding; A randomized controlled trial. BJOG Jan;124(2): Lemmers M, Verschoor MAC, Rengerink K Oude, Naaktgeboren C, Bossuyt PM, Huirne JAF, Janssen IAH, Radder C, Klinkert ER, Langenveld J, Voet L van der, Siemens FF, Bongers MY, Hooff MH van, Ploeg M van der, Coppus SFPJ, Ankum WM, Mol BWJ. MisoREST: Surgical versus expectant management in women with an incomplete evacuation of the uterus after misoprostol treatment for miscarriage: A cohort study. European Journal of Obstetrics and Gynecology and Reproductive Biology 2017;211: Lemmers M, Verschoor MAC, Overwater K, Bossuyt PM, Hendriks D, Hemelaar M, Schutte JM, Adriaanse AH, Ankum WM, Huirne JAF, Mol BWJ. Fertility and obstetric outcomes after curettage versus expectant management in randomised and non-randomised women with an incomplete evacuation of the uterus after misoprostol treatment for miscarriage. European Journal of Obstetrics and Gynecology and Reproductive Biology 2017;211: L.L. Nieuwenhuis, I de Keizer, B Stoelinga, K Demissi, JWR Twisk, WJK Hehenkamp, HAM Brölmann, JAF Huirne. Fibroid vascularisation assessed with 3D Power Doppler is a predictor for uterine fibroid growth. Nieuwenhuis LL, Keizer AL, Stoelinga B, Twisk JW, Hehenkamp WJ, Brölmann HA, Huirne JA. BJOG Feb 17. doi: / [Epub ahead of print] 82. AB Hooker, R de Leeuw, E Bakkum, AL Thurkow, P van de Ven, JM van de Ploeg, H van Vliet, M Bongers, M Hanstede, HAM Brölmann, JAF Huirne. Prevention of Adhesions Post (spontaneous) Abortion (PapaStudy); a randomised controlled trial evaluating application of hyaluronic acid. Fertil Steril Apr 6. pii: S (17) L vd Voet, M.BijdeVaate, HAM Brölmann, S Veersema, JAF Huirne. Factors associated with niche development and related symptoms. Eur J Obstet Gynecol Reprod Biol Apr 5;213: LL Nieuwenhuis, FJR Hermans, AJM BijdeVaate, MMG Leeflang, HAM Brölmann, BWJ Mol, TJ Clark, JAF Huirne. Three-dimensional saline infusion sonohysterography for the diagnosis of focal intracavitary lesions. Cochrane Database Syst Rev May 5;5:CD I de Milliano, D van Hattum, JCF Ket, JAF Huirne, WJK Hehenkamp. Endometrial changes as an effect of ulipristal acetate use: a systematic review. Eur J Obstet Gynecol Reprod Biol Apr 28;214: Review. 86. E van der Meij, HP van der Ploeg, B van den Heuvel, B Dwars, WJHJ Meijerink, HJ Bonjer, Huirne JAF, Anema JR. Assessing postoperative recovery by using an accelerometer; a proof of concept study. BMC Surgery BMC Surg May 12;17(1):56. doi: /s L vd Voet, S.Veersema, A.Timmermans, HAM Brölmann, JAF Huirne. Niches in a population undergoing a hysteroscopy because of Essure placement. Eur J Obstet Gynecol Reprod Biol May 3;214: E.vd Meij, EVA Bouwsma, Baukje van den Heuvel, HJ Bonjer, JR Anema, JAF Huirne. Survey Using e-health in perioperative care: a survey study investigating shortcomings in current perioperative care and possible future solutions. BMC Surg May 23;17(1):61. doi: /s C Nikkels, AJMW Vervoort, BW Mol, WJK Hehenkamp, JAF Huirne, HAM Brölmann. 24/3/18 European Union, Page 6 / 12

7 Laparoscopic resection of uterine caesarean scar ( niche ); staging of innovation in the IDEAL classification based on a review of the literature. Eur J Obstet Gynecol Reprod Biol Jun 23;215: doi: /j.ejogrb [Epub ahead of print] Review. 90. M El Alili, JM van Dongen, JAF Huirne, MW van Tulder, JE Bosmans. Tread cautiously when interpreting results from economic evaluations in obstetrics and gynaecology; a methodological systematic review. Pharmacoeconomics Jul 3. doi: /s [Epub ahead of print] Review. 91. SJ Dedden, PMA Geomini, JAF Huirne, MY Bongers. Vaginal and Laparoscopic hysterectomy as an outpatient procedure: a systematic review. Eur J Obstet Gynecol Reprod Biol Jul 22;216: doi: /j.ejogrb [Epub ahead of print] 92. Lambalk CB, Banga FR, Huirne JA, Vd Veen, Van Wely, Homburg R, Lambalk CB. Long GnRH agonist versus Oral contraceptive pretreated GnRH antagonists in IVF, a systematic review. Hum Reprod Update Sep 1;23(5): L vd Voet, S.Veersema, H.Brölmann, JAF Huirne. Changes in Uterine scar during the First Year after a Caesarean Section: A Prospective Longitudinal Study. Gynecol Obstet Invest Sep 29. doi: / [Epub ahead of print] 94. I. de Milliano, M. Twisk, JCF Ket, JAF Huirne, WJK Hehenkamp. Pre-treatment prior to laparoscopic and laparotomic myomectomy: a systematic review and meta-analysis. (re-submitted. PLoS One Oct 16;12(10):e doi: /journal.pone ecollection AM de Bruijn,M Smink, JAF Huirne, P Lohle, J Twisk, L Schoonmade, WJK Hehenkamp. Uterine artery embolization for the treatment of adenomyosis: a systematic review and meta-analysis. J Vasc Interv Radiol Oct 9. pii: S (17) doi: /j.jvir [Epub ahead of print] Review. 96. JAF Huirne, SI Stegwee, L van der Voet, CJM de Groot, WJK Hehenkamp, HAM Brölmann. Letter to the editor UOG on the article Risk of cesarean scar defect in single- versus double-layer uterine closure: a systematic review and meta-analysis of randomized controlled trials. Ultrasound Obstet Gynecol Nov;50(5): doi: /uog JAF Huirne, AJMW Vervoort, R.A. de Leeuw, HAM Brölmann, WJK Hehenkamp. Laparoscopic niche resection, a step-by-step tutorial. Eur J Obstet Gynecol Reprod Biol Oct 24;219: Lemmers M, Verschoor MAC, Opmeer BC, Bossuyt PM,, Radder C, Klinkert ER, Langenveld J, Siemens F, Geomini P, Jansen CAH, Huirne JAF, Mol BWJ, Ankum WM, Bosmans JE, on behalf of the MisoREST study group. Cost- effectiveness of curettage versus expectant management in women with an incomplete evacuation of the uterus after misoprostol treatment for first trimester miscarriage. Acta Obstet Gynecol Scand Dec 20. doi: /aogs [Epub ahead of print] 99. Stegwee SI, Jordans IPM, van der Voet LF, van de Ven PM, Ket JCF, Lambalk CB, de Groot CJM, Hehenkamp WJK, Huirne JAF. Uterine Caesarean Closure Techniques Affect Ultrasound Findings and Maternal Outcomes: a Systematic Review and Meta-Analysis. BJOG Dec 7. doi: / [Epub ahead of print] 100. Berkhout RP, Lambalk CB, Huirne J, Mijatovic V, Repping S, Hamer G, Mastenbroek S. Highquality human preimplantation embryos actively influence endometrial stromal cell migration. J Assist Reprod Genet Dec 28. doi: /s z. [Epub ahead of print] 101. EVA Bouwsma, T.Vonk Noordegraaf, R.de Vet, H.Anema, J.Huirne. Using patient data to optimize an expert-based guideline on convalescence recommendations after gynecological surgery: a prospective cohort study. BMC Surg Dec 6;17(1):129. doi: /s Lambalk CB, Banga FR, Huirne JA, Vd Veen, Van Wely, Homburg R, Lambalk CB. Letter to the editor concerning comments by Kolibianakis et al 2017 accounting GnRH agonist versus Oral contraceptive pretreated GnRH antagonists in IVF, a systematic review. Hum Reprod Update Dec 29. doi: /humupd/dmx ML Tasma, WH Hehenkamp WJ, PM Geomini, MY Bongers, S Veersema, PJ van Kesteren, E Tromp, JA Huirne, GC Graziosi. Misoprostol for cervical priming prior to hysteroscopy in postmenopausal or nulliparous women; a multi-centre randomised placebo controlled trial BJOG Jan;125(1): doi: / Epub 2017 Mar E van der Meij, J.A.F Huirne, A.D ten Cate, HBAC Stockmann, P.C Scholten, P.H.P Davids, H.J Bonjer, J.R Anema. Perioperative EHealth Program To enhance Postoperative Recovery After Abdominal Surgery: Process Evaluation Alongside A Randomized Controlled Trial. J Med Internet Res Jan 2;20(1):e1. doi: /jmir /3/18 European Union, Page 7 / 12

8 105. EVA Bouwsma, H.Anema, H.Brolmann, P.van Kesteren, S.Schaffoort, J.Huirne. The implementation of an internet-based peri-operative care program to enhance post-operative recovery in gynaecologic patients: a stepped-wedged cluster randomised trial. BMJ Open Jan 30;8(1):e doi: /bmjopen EVA Bouwsma, J.Huirne, J.Bosmans, H.Brolmann, P.van Kesteren, S.Schaffoort, H.Anema. The Cost-effectiveness of an internet-based peri-operative care program to enhance post-operative recovery in gynaecologic patients. BMJ Open Jan 21;8(1):e doi: /bmjopen AM de Bruijn, PNM Lohle, JAF Huirne, J de Vries, M Twisk. QUESTA-Trial Group, WJK Hehenkamp. Uterine artery embolization versus hysterectomy in the treatmentof symptomatic adenomyosis:design of the randomized QUESTA trial. JMIR Res Protoc 2018; 7(3):e E. van der Meij, JR Anema, JAF Huirne, CB Terwee. Using PROMIS for measuring recovery after abdominal surgery: a pilot study. B MC Health Serv Res Feb 20;18(1):128. doi: /s AJMW Vervoort, J Vissers, W Hehenkamp, HAM Brölmann and JAF Huirne. Laparoscopic niche resection, six months follow-up of 101 women; surgical outcome, symptom reduction and ultrasound findings. BJOG Feb;125(3): Keizer AL, Nieuwenhuis LL, Twisk JWR, Huirne JAF, Hehenkamp WJK, Brölmann HAM. Role of 3-Dimensional sonography in the Assesssment of Submucous Fibroids: A Pilot Study. J Ultrasound Med Jan;37(1): doi: /jum Epub 2017 Aug LL Nieuwenhuis, WJK Hehenkamp, HAM Brölmann, JAF Huirne. 3D power Doppler in uterine fibroids; influence of gain, cardiac cycle and off-line measurement techniques. J Obstet Gynaecol Jan;38(1): doi: / Epub 2017 Aug AJMW Vervoort, LF Van der Voet, WJK Hehenkamp, AL Thurkow, CM Radder, PJM van Kesteren, H Quartero, W Kuchenbecker, M Bongers, P Geomini, LHM de Vleeschouwer, MHA van Hooff, H van Vliet, S Veersema, WB Renes, K Oude Rengerink, HAM Brölmann BWJ Mol, JAF Huirne. Hysteroscopic resection of uterine caesarean scar defect (niche) in women with abnormal bleeding, six months follow-up of a randomized controlled trial. BJOG Feb;125(3): Accepted 113. Jordans, IPM, de Leeuw R, Stegwee SI, Amso NN, Barri-Soldevila PN, van den Bosch T, Bourne, T, Brolmann HAM, Donnez O, Dueholm M, Hehenkamp WJK, Jastrow N, Jurkovic D, Mashiach, R, Naji O, Streuli I, Timmerman D, vd Voet LF, Huirne JAF. Practical guideline for ultrasonographic niche: a modified Delphi method among European experts (accepted JOUG) Bookchapters and proceedings 1. Huirne JAF, Seppenwoolde Y, Quartero HWP, Peters MJ. Antenatal magnetocardiographic diagnosis of conduc ting disturbances. In Recent advances in biomagnetism. Editors: T.Yoshimoto et al. Tohoku University press, Sendai, Japan, 1999; Stinstra JG, Krooshoop HJG, Muis B, Huirne JAF, Quartero HWP, Peters MJ. The influence of the vernix caseosa on fetal cardiograms. In Recent ad vances in biomagnetism. Editors: T. Yoshimoto et al. Tohoku University press, Sendai, Japan, 1999; Huirne JAF, Lambalk CB, Janssens R, Schoemaker J. GnRH Agonists versus Antagonists, where are we today? In Controverses in Obstetrics and Gynaecology. Editors: Z. Ben-Rafael and Z Shoham. Monduzzi Editore Bologna Italy, 1999; Huirne JA, Schats R. The use of GnRH agonists. In Textbook of assisted reproductive techniques laboratory and clinical perspectives. Editors: DK Gardner, A Weissman, C Howles and Z Shoham. 2004; Brolmann HAM, Hoozemans D, Huirne JAF. Behandelingsmodaliteiten myoom. Reproductieve geneeskunde, gynaecologie en obstetrie anno 2009: Huirne JAF, Catshoek R, Brolmann HAM. Van totale naar de subtotale laparoscopische hysterectomie. En waarom niet? Reproductieve geneeskunde, gynaecologie en obstetrie anno 2009: Brolmann HAM, van Kesteren PJM, Janssen P, Huirne JAF. Technieken voor laparoscopische coagulatie; hoe goed moet hemostase zijn? Reproductieve geneeskunde, gynaecologie en obstetrie anno 2009: JAF Huirne, L.van der Voet, A.J.M. BijdeVaate, S.Veersema, H.A.M. Brölmann. De behandeling van een niche in het Sectio litteken. Reproductieve geneeskunde, gynaecologie en obstetrie anno 2011: JAF Huirne, P. Van Kesteren, T. Vonk Noordegraaf, H.A.M. Brölmann. Moet het nog minimaal 24/3/18 European Union, Page 8 / 12

9 invasiever, wie wordt er beter van? Reproductieve geneeskunde, gynaecologie en obstetrie anno 2011: A.J.M. Bij de Vaate, H.A.M. Brölmann, L.F. van der Voet, J.W. van der Slikke, S. Veersema, JAF Huirne. Echoscopie van het sectiolitteken: Relatie tussen de niche en abnormaal uterien bloedverlies Reproductieve geneeskunde, gynaecologie en obstetrie anno 2011: WH.Hehenkamp, H.Brölmann, JAF Huirne. Uterine Artery Embolization and new ablation techniques in Uterine Myoma, page in Myomectomy and Minimal invasive Treatments, Tinelli and Malvasi (eds), Springer HAM Brölmann, JH van Waesberghe, W Hehenkamp, JAF Huirne. Imaging of Myomas, Uterine Myoma, page in Myomectomy and Minimal invasive Treatments, Tinelli and Malvasi (eds), Springer WJK Hehenkamp, JAF Huirne, HAM Brölmann. Preoperatieve voorbehandeling met Ulipristal van een grote uterus myomatosus is vrijwel nooit geïndiceerd. Reproductieve geneeskunde, gynaecologie en obstetrie anno 2015, Slager (ed), dchg 2015: LL Nieuwenhuis, MAJ BijdeVaate, WJK Hehenkamp, MW Heymans, MWM van Baal, HAM Brölmann, JAF Huirne. Diagnostische en klinische waarde van 3D GIS toegevoegd aan 2D GIS bij de evaluatie van intra-cavitaire afwijkingen. Reproductieve geneeskunde, gynaecologie en obstetrie anno 2015, Slager (ed), dchg 2015: EVA Bouwsma, A Vonk Noordegraaf, HAM Brölmann, JR Anema, JAF Huirne. Werkhervatting na gynaecologische chirurgie ondersteuning middels e-health werkt! Reproductieve geneeskunde, gyanecologie en obstetrie anno 2015, Slager (ed), dchg 2015: JAF Huirne, M.BijdeVaate, L.vander Voet, WJK Hehenkamp, HAM Brölmann. Niche is een klinisch probleem. Reproductieve geneeskunde, gynaecologie en obstetrie anno 2015; JAF Huirne, M.BijdeVaate, L.vander Voet, WJK Hehenkamp, HAM Brölmann. Behandeling van de niche anno Reproductieve geneeskunde, gynaecologie en obstetrie anno 2015, Slager (ed), dchg 2015: JAF Huirne, M BijdeVaate, L vde Voet, M.Witmer, HAM Brölmann. Diagnostic methods, risk factors of niches, related symtoms and therapies, page in Minimally Invasive gynecological Surgery, Olav Istre (eds), Springer L vd Voet, S Veersema, BC Schoot, JAF Huirne. Unusual hysteroscopic situations: Caesarean niche and retained placental tissue. Diagnostic and operative hysteroscopy, RCOG, Justin Clark (eds), Cambridge University press Nieuwenhuis LL, Keizer AL, Stoelinga B, Twisk JWR, Hehenkamp WJK, Brölmann HAM, Huirne JAF. Toegevoegde waarde 3D-beoordeling uteriene pathologie. In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Hehenkamp WJK, Groenman F, de Leeuw RA, Brölmann HAM, Huirne JAF. Niet-chirurgische myoombehandeling anno In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Brölmann HAM, Huirne JAF, Hehenkamp WJK, Groenman F. Morcellatie: moet het nu allemaal in de zak? In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Hooker AB, Brölmann HAM, Huirne JAF. Adhesiepreventie bij zwangerschapsresten of placentaresten. In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Huirne JAF, Vervoort AJMW, Uittenbogaart LB, Brölmann HAM, van der Voet LF, Hehenkamp WJK. De etiologie van niche-ontwikkeling. In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Nikkels C, Vervoort AJMW, Mol BW, Hehenkamp WJK, Huirne JAF, Brölmann HAM. In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Huirne JAF, Hehenkamp WJK, Brölmann HAM. Myoom of sarcoom? Echoscopische aanknopingspunten. In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Hooker AB, de Leeuw R, Brölmann HAM, Huirne JAF. Zijn intra-uteriene adhaesies na verwijdering van zwangerschapsresten te voorkómen? In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Vervoort AJMW, van der Voet LF, Hehenkamp WJK, Brölmann HAM, Huirne JAF. Hysteroscopische nicheresectie bij vrouwen met klachten van postmenstruele spotting. In: 24/3/18 European Union, Page 9 / 12

10 Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Huirne JAF, Vervoort AJMW, Nikkels C, Vissers J, Brölmann HAM, Hehenkamp WJK. De laparoscopische nichebehandeling. In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Van der Voet LF, Jordans IPM, Stegwee S, de Leeuw R, Hehenkamp WJK, Huirne JAF. Echoscopische beoordeling van niches. In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Lemmers M, Verschoor MAC, Oude Rengerink K, Naaktgeboren C, Opmeer BC, Bossuyt PM, Huirne JAF, Janssen CAH, Radder C, Klinkert ER, Langenveld J, van der Voet L, Siemens F, Geomini P, van Hooff MH, van der Ploeg JM, Coppus SFPJ, Ankum WM, Mol BWJ. Miskraam: wanneer curetteren, hoe en wat zijn de gevolgen? In: Reproductieve geneeskunde, Gynaecologie en Obstetrie anno 2017, Editor: E. Slager, Heemstede, blz Dutch publications 1. Albers JF, Gerstenbluth I, Huirne JAF, Smits IMH. Prevalentie schattingen van chronische aandoeningen op Curaçao; zelfrapportage versus huisartsen registratie. Tijdschrift voor Sociale Gezondheidszorg 1996: 74; Quartero HWP, Huirne JAF, Seppenwoolde Y, Peters MJ. Foetale magneti schecardiografie (fmcg) bij ritmestoornissen van de foetus. Nederlands Tijd schrift voor Obstetrie & Gynaecologie 1998: 111; Huirne JAF, Schats R, Hompes PGA, Lambalk CB. Mechanism of action of GnRH analogues. Tijdschrift voor fertiliteitsonderzoek 2002: 2; Huirne JAF, Lambalk CB - GnRH-agonisten en antagonisten voor IVF-behandeling en andere indicaties. Freya Magazine 2002: 18; Huirne JAF, Lambalk CB. GnRH-antagonist goed alternatief voor lang agonisten-protocol. Fertiliteit in de praktijk 2003;1:19 6. Janssen PF, Van der Houwen C, Huirne JAF, Kluivers KB, Brolmann HAM. De laparoscopische hysterectomie en urologische letsels; herkennen en voorkómen. Nederlands tijdschrift voor Obstetrie & Gynaecoogie 2007: 120; Maarssen M, BijdeVaate AJM, Huirne JAF, Brölmann HAM, De maandkalender; een hulpmiddel voor een efficiënte menstruatieanamnese. Nederlands tijdschrift voor Obstetrie & Gynaecologie 2011; 124: Van Kesteren PJM, Adriaanse AH, Geomini PMJ, Huirne JAF, Van der Wijden CL, Arents NLA, Van Dam AP, Van Barneveld TA, La Chapelle CF. Pelvic inflamitory disease en tuba ovarieel abces. Richtlijn NVOG LB van Rijssen, PJ van Empel, JA Huirne, HJBonjer, MA Cuesta, WJHJ Meijerink. Simulatieonderwijs in de Minimaal Invasieve Chirurgie: Advanced Suturing Course. Ned Tijdschr Geneeskd. 2012;156: A JAF Huirne, GLM Bremer, J Wijma. Implementatie van Ulipristal, is de kwaliteitscirkel doorlopen? Nederlands Tijdschrift voor Obstetrie en Gynaecologie 2013; 06: HAM Brölmann, C Radder, JAF Huirne. WGE: tijd voor een terugblik. Nederlands Tijdschrift voor Obstetrie en Gynaecologie 2013; 126: J.Huirne, MA Oudijk, A Hoek, JP de Bruin namens het NVOG Consortium 2.0 bestuur. Inclusies nodig om deadlines te halen. NTOG 2014;7: HAM Brölmann, WJK Hehenkamp, JAF Huirne. Heeft het myoom zijn onschuld verloren? NTOG 2014;7: J van Keizerswaard, NM van Mello, WHM Karsdorp, JAF Huirne. Vitale nichezwangerschap. NTOG 2017; 130: NM van Mello, J van Keizerswaard, JAF Huirne. Nichezwangerschap: een review van de behandelopties. NTOG 2017;130: M. Lemmers, M.A.C. Verschoor, W.M. Ankum, J.A.F. Huirne, B.W.J. Mol. Optimalizatie van zorg rondom eerste trimester miskraam; een richtlijn is onontbeerlijk. NTOG 2017 Projects Grants 2008 Grant (applicant), multidisciplinary recommendations and patient weblog for resumption of work activities after gynaecological surgery, Kennisbeleid, Kwaliteit Curratieve Zorg richtlijn has been 24/3/18 European Union, Page 10 / 12

11 awareded by ZonMw ( ) 253kE 2010 Grant (applicant), the cost-effectiveness of a transmural peri-operative care program for gynaecology, DoelmatigheidsOnderzoek 2010, (E&K) has been awarded by ZonMw ( ), 439kE 2011 Grant proposal (applicant), hysteroscopic resection of uterine cesarean scar defect (niche) in patients with abnormal bleeding, a randomized controlled trial, DoelmatigheidsOnderzoek, 2011, Vroege Evaluatie van Medische Innovatie (VEMI), has been awarded by ZonMw ( ), 250kE 2011 Grant proposal (applicant), Assistent-geneeskundige in opleiding tot klinisch onderzoeker (AGIKO) Eva Bouwsma on the project the cost- effectiveness of a transmural peri-operative care program for gynaecology, has been awarded by ZonMw ( ) 64kE 2011 Grant proposal (co-applicant), What should be done in women with an incomplete evacuation of the uterus after treatment with misoprostol for miscarriage? An analysis of costs and effects. DoelmatigheidsOnderzoek, (E&K) has been awarded by ZonMw ( ) 350kE 2011 Grant proposal (project-member), RCT comparing the levonorgestrel releasing intrauterine system (Mirena) versus endometrial ablation (MIRA)? an analysis of costs and effects. DoelmatigheidsOnderzoek (E&K) has been awarded by ZonMw ( ), 444kE 2011 Grant Olympus, pilotstudy te evaluate the results of laparoscopic niche resections in symptomatic patients. 10kE 2011 Grant Samsung, the additional value of sonoelastography in the evaluation of fibroids with MRI as reference test. 18kE 2014 Grant proposal (applicant), substitution of usual perioperative care by ehealth & ICT: a stepped wedge cost-effectiveness analysis alongside a cluster randomised controlled trial ZonMw ( ), 397kE 2014 Grant MYOMEX trial (co-applicant): (Cost)effectiveness of Ulipristal versus GnRHa treatment before laparoscopic fibroid removal. Gideon Richter150kE Adenomyose embolysation trial (CeleNova) (co-applicant): Embolisation versus hysterectomy in the treatment of adenomyosis. 233kE 2015 Grant proposal (applicant), 2CLOSE study: The effectiveness of 2 layer closure of the uterine CS scar compared to one layer on postmenstrual spotting and fertility in relation to niche developement. DoelmatigheidsOnderzoek, (E&K) has been awarded by ZonMw. 395kE 2015 Innovation grant (applicant) For the development of an discharge planner and app. 55kE VUmc Innovation grant (co-applicant) for the development of a discrete choice model and interactive webportal (webapp) for cryopreservation of oocyts or embryo s. 65kE VUmc and AMC Take-off subsidie ZonMw, opzetten ikherstel spinoff. 55kE 2017 Innovation grant (co-applicant) for inventarisation possibilities Uterine transplantations. 60kE VUmc The predictive value of vascularity measured with US on fibroid growth and therapy response. Samsung. 120KE Grant proposal (co-applicant) Ulipristal versus standard surgical treatment in symptomatic uterine fibroids. DoelmatigheidsOnderzoek, (E&K) has been awarded by ZonMw ( ), 389kE Memberships Referee scientific journals Surgical endoscopy Gynaecological endoscopy European journal of Obstetrics and Gynaecology and reproductive biology Journal of clinical ultrasound Human Reproduction Human Reproduction Update Journal of Ultrasound in Obstetrics and Gynaecology Other Relevant Information Management functions: 24/3/18 European Union, Page 11 / 12

12 2014- present Vice-chairman a.i. Divisie III (women and children), VUmc present Head of the subdivision Gynaecology VUmc Member of the executive board European Society of Endoscopic Surgery (ESGE) President of the Dutch Society of Gynaecological Endoscopy (WGE), secretary from Board member Scientific Committee of the Dutch Society of Obstetrics and Gynaecology (NVOG) Boardmember Nederlandse Vereniging van Endoscopische Chirurgie (NVEC) Advisory board POMT, Dutch registration of surgical complications in gynaecology Training: present Coordinator advanced laparoscopic courses cluster AMC/VUmc present Faculty Advanced suturing course, Amsterdam present Faculty Congress for infertility, obstetrics and gynaecology, Rotterdam present Faculty International Endoscopic Oslo winter congress present Faculty National imaging course, Amsterdam present Faculty National course on fibroids, Amsterdam present Faculty Get-Up, international course (4 days) for advanced laparoscopic surgery Faculty Provisio; international 3D ultrasound course, BSGI 3D workshops Faculty Cobra congress Faculty NVEC; Dutch Society for Endoscopic surgery 2014 Co-chair scientific program ESGE congress 2016 Faculty National Essure removal course Scientific Awards 2010 Price winning abstract ISUOG 2010:, Bij de Vaate AJM, Brölmann HAM, Huirne JAF. Ultrasound evaluation of the caesarean scar: Relation between a niche and postmenstrual spotting 2010 Postoperative recovery research has been nominated for the Societal impact award EMGO Price winning presentation Gynaecongres 2012 Den Haag. Vonk Noordegraaf, J.R. Anema, H.A.M. Brölmann, W. van Mechelen, J.A.F. Huirne. Ikherstel.nl: effectiviteit van e-health interventie op hervatting van (werk)activiteiten na een gynaecologische operatie 2012 Winner of the internationale ICOH congres de Liberty Mutual Work Disability Prevention Research Award to recognize outstanding research in work disability prevention Winner young scientist Award Dutch Society Gynaecological Endoscopy 2013; Hooker AB, Lemmers M, Thurkow AL, Heymans MW, Opmeer BC, Brölmann HA, Mol BW, Huirne JA Nomination Achmea Quality Award: ik herstel project. A. Vonk Noordegraaf, E.V.A. Bouwsma, J.A.F. Huirne, H.A.M. Brölmann, W. van Mechelen, R. Anema 2015 Oeuvre award; profiel prijs VUmc; Ikherstel team VUmc Josefprijs, wetenschapsprijs Deventer Ziekenhuis. For the impact of the HYSNICHE study 24/3/18 European Union, Page 12 / 12