Citation for published version (APA): Eijkelkamp, M. F. (2002). On the development of an artificial intervertebral disc s.n.
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1 University of Groningen On the development of an artificial intervertebral disc Eijkelkamp, Marcus Franciscus IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2002 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Eijkelkamp, M. F. (2002). On the development of an artificial intervertebral disc s.n. Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date:
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4 ON THE DEVELOPMENT OF AN ARTIFICIAL INTERVERTEBRAL DISC Mark Eijkelkamp
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6 Rijksuniversiteit Groningen ON THE DEVELOPMENT OF AN ARTIFICIAL INTERVERTEBRAL DISC Proefschrift ter verkrijging van het doctoraat in de Medische Wetenschappen aan de Rijksuniversiteit Groningen op gezag van de Rector Magnificus, prof. dr. F. Zwarts, in het openbaar te verdedigen op woensdag 27 november 2002 om uur door Marcus Franciscus Eijkelkamp geboren op 17 september 1970 te Dalfsen
7 Promotor: Referenten: Prof. Dr. J.R. van Horn Dr. G.J. Verkerke Dr. A.G. Veldhuizen Dr. J.M. Huyge Beoordelingscommissie: Prof. dr. H Busscher Prof. dr J de Bont Prof dr. ir F Baaijens
8 Paranimfen: Peter van Os Paul Eijkelkamp
9 Dit Proefschrift is mede mogelijk gemaakt door: The pictures at the cover of this thesis are made at Philips Medical Systems in Best. Copyright 2002: M.F. Eijkelkamp, Groningen, The Netherlands. All rights reserved. No part of this publication may be reprintend or utilized in any form by any lelectronic mechanical or other means, now known or hereafter invented, included photocopying and recording, or in any information storage or retrieval system, without permission of the copyright owner ISBN
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12 Voorwoord Voorwoord Mijn onderzoek naar een tussenwervelschijfprothese is gestart in januari 1995 (een strenge winter dus lekker veel schaatsen). Het onderzoek werd uitgevoerd bij de afdeling Artificial Organs. Gerhard Rakhorst was het hoofd daarvan en Bart Verkerke de projectleider. We zaten in het souterrain van Bloemsingel 10, muf, maar wel erg gezellig. Bart Verkerke was mijn begeleider, vooral aan hem heb ik veel te danken qua begeleiding en het corrigeren van mijn output. Later werden we ondergebracht bij de afdeling Biomedical Engineering van professor. Henk Busscher en verhuisden we naar de flat aan de Anthonius Deusinglaan 1. Het onderzoek werd samen met de afdeling orthopedie van het Academisch Ziekenhuis Groningen uitgevoerd, waar prof. Jim van Horn mijn promotor was. Samen met de rugspecialist Albert Veldhuizen zorgde hij voor de medische begeleiding De experimenten, beschreven in hoofdstuk vier, zijn uitgevoerd in samenwerking met de afdeling Anatomie, die toen nog in een van de mooie oude gebouwen van de medische faculteit gehuisvest waren. Later gingen ze ook over naar de "Vrouwenkliniek" waar wat meer ruimte voor experimenten was. De hulp van Noor Mouton en vooral John Legrand is mij zeer dankbaar geweest. Ook de hulp van Bert Otten (toen nog werkzaam bij de Medische Fysiologie) voor raad en het Elite Systeem was onmisbaar. John Cheung voerde het snijwerk uit en Arjan van der Plaats (Arie) en stagiaires en afstudeerders waren uitermate behulpzaam bij de logistiek. Voor het onderzoek beschreven in hoofdstuk 6 gaat mijn dank uit naar Jan Hayen, met wie ik dit onderzoek heb gedaan. Dat hij voor zijn bijdrage in Duitsland een prijs heeft gekregen deed mij veel goed. Tini Roek heeft erg veel werk verricht om mijn manuscript bij de leescommissie te krijgen en om allerhande andere karweitjes uit te voeren. De mechanische werkplaats en vooral Jan Hoks stond altijd klaar om mijn ontwerpen te maken. Het onderzoek werd in samenwerking met de vakgroep werktuigbouwkunde van Frank Baaijens de technische universiteit Eindhoven uitgevoerd. Vooral Rene van Donkelaar en Jacques Huyge hebben veel werk voor het onderzoek verricht. Ook wil ik alle medewerkers van de Disciplinegroep Biomedical Engineering bedanken voor de gezelligheid, met name Marjan, Wim, Albert, Martin, Ed en Arie, en de anderen van de afdeling Orgaantechnologie die ik bijna gedurende mijn hele promotie heb meegemaakt, en kamergenoot Fernando. 11
13 Voorwoord Voor de laatste loodjes om het proefschrift bij de drukker te krijgen wil ik Poppe Onrust van Philips Medical Systems best bedanken voor het gebruik van de computer en software. Verder mag ik natuurlijk niet vergeten de vrienden van Klein Verzet waarmee ik nog elk jaar ga Atb-en in de Ardennen en de leden van Tandje Hoger uit Groningen, met wie ik veel kilometertjes met veel plezier heb kunnen fietsen. En vooral niet te vergeten: Sybrich. 12
14 Contents Contents Voorwoord Error! Bookmark not defined. Contents 13 Chapter 1 Introduction Error! Bookmark not defined. Chapter 2 defined. Chapter 3 Requirements for an artificial intervertebral discerror! Bookmark not The geometry of the human paraspinal muscles with the aid of three-dimensional computed tomography scans and 3-Space Isotrak Error! Bookmark not defined. Chapter 4 Measurement of the compliance of the human torsoerror! Bookmark not defined. Chapter 5 The geometry and shape of the human intervertebral discerror! Bookmark not defined. Chapter 7 Improving the fixation of an artificial intervertebral discerror! Bookmark not defined. Chapter 9 Discussion Error! Bookmark not defined. Chapter 10 Summary Chapter 11 Samenvatting Error! Bookmark not defined. Error! Bookmark not defined. 13
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