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1 Cover Page The handle holds various files of this Leiden University dissertation. Author: Dekker, Jan Willem Title: Risk and outcome in colorectal cancer surgery Date:

2 Appendices 203

3 Dankwoord Dankwoord Een proefschrift! De weg en het doel, alle clichés zijn waar. Ik kijk terug op een zeer leerzame en ook leuke tijd. Het is nu vooral de goede herinnering aan prettige samenwerking die vage ergernissen doet vergeten. Promoveren is teamwork, daarom wil ik graag een aantal mensen in het bijzonder danken die ertoe hebben bijgedragen dat u nu dit boekje voor u hebt. Allereerst mijn promotor, Professor Tollenaar, beste Rob, als wij overleg hadden over de opzet en de vorderingen van mijn proefschrift was ik telkens weer verrast hoe snel jij tot de kern van de zaak kan doordringen. Ik heb veel geleerd van jouw manier om snel te schakelen Gerrit-Jan Liefers, co-promotor, zonder jou was het zeker niet gelukt. Jouw luisterend oor en jouw altijd positieve commentaar waren een enorme stimulans voor mij. Ik hoop dat we samen met onze families nog vaak op Schouwen zullen genieten van een heel behoorlijk glaasje met een fijne Oosterscheldekreeft of een zelfgeplukt oestertje. Speciale dank aan alle mede auteurs voor de inspirerende discussies en natuurlijk hun hulp als het nodig was. Alexander en Koen dank dat jullie me over een dood punt heen hebben geholpen. Hein bedankt dat jij soms een baken was in statistische mist. Colette en Esther onze samenwerking kwam voor mij precies op het goede moment. Esther het is eigenlijk een wonder dat je ook nog tijd had voor jouw eigen proefschrift. Lydia dank voor jouw hulp en het aanleveren van data. Els, als medeclinicus toch fijn jouw snelle wetenschappelijke carrière van dichtbij meegemaakt te hebben. Medeonderzoekers van C11, ondanks onze verschillende levensfasen vond ik het leuk om samen in het zelfde schuitje te zitten. Dank voor jullie enthousiasme. 204

4 Dankwoord Gea, jouw bijdrage aan mijn proefschrift zal niemand ontgaan zijn. Jouw werklust en enthousiasme zijn een gouden combinatie. Ik hoop nog vaak tikkie-takkie met je te mogen doen en ik ben erg blij dat jij straks mijn paranimf bent. Thea en Sanne dank voor het meedenken en regelen als het erop aan kwam. Janneke bedankt voor je stressbestendigheid en een boekje om trots op te zijn zelfs als niemand het leest. Oma Jos dank voor jouw onvoorwaardelijke inzetbaarheid als er werk af moest. Annelies, Hans en mamma, blood is thicker than wine. Onze innige band is de afgelopen moeilijke tijd alleen maar hechter geworden. Dank voor jullie onvoorwaardelijke steun en kracht. Het is erg jammer dat pa er niet meer bij is. Hij is altijd een voorbeeld voor mij geweest en ik heb veel aan hem te danken. Maar we hebben het niet laten liggen en wist je dat wijn ook gemaakt wordt van druiven? Hans, fijn dat ik altijd op jou kan rekenen. Een goed gevoel om jou straks als paranimf achter me te hebben staan. Kim, samen met jou blijft een feest. Samen bij de molen, samen op de fiets, samen naar tentamen, samen co, samen de eed, samen voor de wet, samen in de kerk, samen drie geweldige kinderen en nu dan samen promoveren. Jij bent niet alleen de liefde van mijn leven, maar ook mijn beste vriend. Dankjewel. 205

5 Curriculum Vitae Curriculum Vitae Jan Willem Dekker was born on may 31st 1972 in Veenendaal, the Netherlands, as the son and grandson of local general physicians. He graduated from the Christelijk Lyceum Veenendaal in1990. The same year he started medical school at the University of Leiden, where he graduated in1998. After graduation he started working as a house officer in the obstetrics and gynaecology department of the Westeinde Hospital in The Hague, under supervision of Dr. J.P. Dörr. Here he learned what it means to be a medical doctor. In 2000 he decided to take up surgery at the Bronovo Hospital in The Hague under supervision of Dr. A.B.B. van Rijn who was a great stimulus to make a career in surgery. In 2001 he started working at Medical Center Haaglanden in The Hague where he began his surgical training under supervision of Dr. J.C.A. de Mol van Otterloo. He continued his training at the Leiden University Medical Center, under supervision of Prof.Dr. O.T.T. Terpstra and later Prof.Dr. J.F. Hamming who made a compelling argument to become a PhD student. After finishing his training in 2008 he took up a fellowship (CHIVO) in Surgical Oncology at the Leiden University Medical Center under supervision of Prof.Dr. R.A.E.M. Tollenaar who also supervised his scientific career. In he worked as a gastro-intestinal surgeon at the Onze Lieve Vrouwe Gasthuis in Amsterdam. Since January 1st 2012 he is practising gastro-intestinal surgery at the Reinier de Graaf Gasthuis in Delft. He is happily married to Kim Boers and has three wonderful children: Tim, Anne Jet and Hidde. 206

6 List of publications List of publications: CBM van den Broek, E Bastiaannet, JWT Dekker, JEA Portielje, AJM de Craen, MAG Elferink, CJH van de Velde, GJ Liefers, E Kapiteijn Time trends in chemotherapy (administration and costs) and relative survival in stage III colon cancer patients - a large population-based study from 1990 to Submitted to European Journal of Cancer JWT Dekker, GA Gooiker, E Bastiaannet, CBM van den Broek, LGM van der Geest, CJH van de Velde, RAEM Tollenaar, GJ Liefers The prolonged impact of the insult of surgery for colorectal cancer in the elderly. Submitted to Journal of the American Geriatric Society JWT Dekker, GA Gooiker, LGM van der Geest, N Kolfschoten, H Struikmans, H. Putter, M Wouters, RAEM Tollenaar Comorbidity as confounding factor in the analysis of mortality, surgical complications and length of stay after surgery for colorectal cancer. Under revision for European Journal of Surgical Oncology GA Gooiker, JWT Dekker, E Bastiaannet, LGM van der Geest, H Struikmans, P Nijenhuis, B Tanis, J WS Merkus, GJ Liefers, MWJM Wouters, CJH van de Velde, RAEM Tollenaar Risk factors for excess mortality in the first year after curative surgery for colorectal cancer (in a population based Dutch cohort). Annals of Surgical Oncology mar 7. Epub ahead of print. Lambooij SLE, JWT Dekker, Bastiaannet E, Tollenaar RAEM, Westendorp RGJ, de Craen AJ Survival of patients with second primary colorectal cancer. Under revision for Annals of Surgical Oncology CBM van den Broek, JWT Dekker, E Bastiaannet, ERP Collette, P Krijnen, AJM de Craen, RAEM Tollenaar, CJH van de Velde, GJ Liefers The survival gap between mid- 207

7 List of publications dle aged and elderly colon cancer patients. Time trends in treatment and survival. Eur J Surg Oncol Oct;37(10): Epub 2011 Jul 23. A Fariña Sarasqueta, ECM Zeestraten, I van Lijnschoten, JWT Dekker, PJK Kuppen, VEPP Lemmens, T van Wezel, HJC Rutten, J Morreau, AJC van den Brule Stage dependent impact of pik3ca kinase domain mutation on survival of colon cancer. Cell Oncol (Dordr) Aug 10. [Epub ahead of print] JWT Dekker, CBM van den Broek, E Bastiaannet, L van de Geest, RAEM Tollenaar, GJ Liefers. Importance of first postoperative year in prognosis of elderly colorectal cancer patients. Annals of Surgical Oncology Jun;18(6): Epub 2011 Mar 29. JWT Dekker, Liefers GJ, Mol van Otterloo JCA de, Tollenaar RAEM Predicting the Risk of Anastomotic Leakage in Leftsided Colorectal Surgery Journal of Surgical Research 2011 Mar;166(1):e Epub 2010 Dec 1. JWT Dekker, Peeters KC, Vahrmeijer AL, Putter H, van de Velde CJH Prognostic capacity of metastatic lymph node ratio in addition to the 7 th edition of the TNM classification. European Journal of Surgical Oncology 2010 Dec;36(12): GA Gooiker, L Veerbeek, LGM van der Geest, JWT Dekker, JWR Nortier, A Marinelli, H Struikmans, MWJM Wouters, RAEM Tollenaar De prestatie indicator irradicaliteit na borstsparende operatie : zuiver zicht op goede zorg? NTVG; 2010; 154: A1142 L Veerbeek, LGM van der Geest, MWJM Wouters, JWT Dekker, MLEA Jansen, JWR Nortier,AWKS Marinelli, RAEM Tollenaar, H Struikmans namens de ziekenhuizen in de IKW regio. Verbeterde registratie van de oncologische zorg door samenwerking tussen ziekenhuizen en de kankerregistratie in de regio van het Integraal Kankercentrum West. Med.Contact 42, 17 okt 2008 dig. 208

8 List of publications JWT Dekker, Lind J, Bloemenkamp KW, Quint WG, Kuijpers JC, van Doorn LJ, de Groot CJ Inherited risk of thrombosis of the fetus and intrauterine fetal death. Eur J Obstet Gynecol Reprod Biol Nov 10;117(1):45-8. Boers KE, JWT Dekker, Yedema CA, Diagnose in Beeld (98). Een vrouw met een verdwenen spiraal. Ned Tijdschr Geneeskd Jul 27;146(30):1412. JWT Dekker, Dongen HPA van, Souverijn JHM, Kerkhof GA. Stress masks constant-routine cortisol rhythms. Jaarboek Ned.Ver voor Slaap-waak onderzoek Sleep-wake research in the Netherlands, vol 7,

9 210

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