Cover Page. The handle holds various files of this Leiden University dissertation.

Maat: px
Weergave met pagina beginnen:

Download "Cover Page. The handle holds various files of this Leiden University dissertation."

Transcriptie

1 Cover Page The handle holds various files of this Leiden University dissertation. Author: Kusters, Maria Antonia Adriana (Maaike) Title: Adaptive immune system and vaccination responses in Down syndrome Issue Date:

2

3 12 CURRICULUM VITAE LIST OF PUBLICATIONS LIST OF ABBREVIATIONS

4 162

5 CURRICULUM VITAE Maaike Rekers-Kusters werd op 6 februari 1981 geboren in het Brabantse Rijkevoort. Maaike woont in Lent, en heeft een heerlijke tuin die ze deelt met haar man André Rekers, de man achter de schermen bij dit proefschrift! Haar favoriete film is Le fabuleux destin d Amélie Poulain. 12 Maaike wist al op jonge leeftijd dat ze dokter wilde worden, hoewel plantkunde, design en architectuur haar ook trokken. Wat voor een dokter, dat was toen nog niet duidelijk. De Aha-erlebnis kwam bij het co-assistentschap Kindergeneeskunde in het Tweesteden-ziekenhuis in Tilburg, met name door het aanstekelijke enthousiasme en de tomeloze toewijding van dokter Jaap van Lier. De eerste stappen in de kindergeneeskunde werden gezet in het Maxima Medisch Centrum in Veldhoven en het Jeroen Bosch Ziekenhuis s-hertogenbosch als artsassistent niet in opleiding (ANIOS). In 2010 kon worden gestart met de opleiding tot kinderarts (opleider T. Mulder) in het MUMC + in Maastricht, de tweede helft van de opleiding wordt vervolgd in het Radboudumc (opleider J. Draaisma) in Nijmegen. Curriculum Vitae Het wetenschappelijk onderzoek werd verricht naast haar full-time klinische werkzaamheden, met als uitvalsbasis het Jeroen Bosch Ziekenhuis onder de bezielende leiding van Dr. Esther de Vries. Na haar opleiding tot kinderarts wil Maaike zich verder specialiseren binnen de immunologie, een tak van sport waar Maaike zeer gepassioneerd over is. 163

6 164

7 LIST OF PUBLICATIONS 1. Kusters MA, Verstegen RH, Gemen EF, de Vries E. Intrinsic defect of the immune system in children with Down syndrome: a review. Clin Exp Immunol 2009; 156 (2): Verstegen RH, Kusters MA, Gemen EF, de Vries E. Down syndrome B-lymphocyte subpopulations, intrinsic defect or decreased T-lymphocyte help? Pediatr Res 2010; 67 (5): Kusters MA, Gemen EF, Verstegen RH, Wever PC, de Vries E. Both normal memory counts and decreased naive cells favor intrinsic defect over early senescence of Down syndrome T- lymphocytes. Pediatr Res 2010; 67 (5): Kusters MA, Jol-Van der Zijde CM, van Tol MJ, Bolz WE, Bok LA, Visser M, de Vries E. Impaired avidity maturation after tetanus toxoid booster in children with Down syndrome. Pediatr Infect Dis J 2011; 30 (4): List of Publications 5. Kusters MA, Jol-Van der Zijde CM, Gijsbers RH, de Vries E. Decreased response after conjugated meningococcal serogroup C vaccination in children with Down syndrome. Pediatr Infect Dis J 2011; 30 (9): Kusters MA, Verstegen RH, de Vries E. Down syndrome: is it really characterized by precocious immunosenescence? Aging Dis 2011; 2 (6): Kusters MA, Bok VL, Bolz WE, Huijskens EG, Peeters MF, de Vries E. Influenza A/H1N1 vaccination response is inadequate in Down syndrome children when the latest cut-off values are used. Pediatr Infect Dis J 2012; 31 (12): Kusters MA, Manders NC, de Jong BA, van Hout RW, Rijkers GT, de Vries E. Functionality of the pneumococcal antibody response in Down syndrome subjects. Vaccine 2013; 31(52):

8 166

9 LIST OF ABBREVIATIONS Ad-REF Reference values from healthy adults ADHS Antibody diluted human serum AMC Age-matched control BD Becton Dickinson CD Cluster of differentiation CMV cytomegalovirus CSR Class switch recombination CVID Common variable immunodeficiency disorders DGS DiGeorge syndrome DS Down syndrome DSCAM Down syndrome cell adhesion molecule ELISA Enzyme-linked immunosorbent assay ENT Ear-nose-throat FACS Fluorescence-activated cell sorting FI Fold Increase FITC Fluorescein isothiocyanate GALT Gut-associated lymphoid tissue GMT Geometric mean titer HBsAg Hepatitis B surface antigen HI Hemagglutination-inhibition HIV Human immunodeficiency virus ICAM-1 Intercellular adhesion molecules-1 IFN Interferon Ig Immunoglobulin IL Interleukin IPD Invasive pneumococcal disease KREC kappa-deleting recombination excision circles LFA-1 Lymphocyte function-associated antigen-1 MAb Monoclonal antibodies MALT Mucosa-associated lymphoid tissue MenC Meningococcal serogroup C conjugate vaccine MFI Mean fluorescence intensity NK Natural killer OPA Opsonophagocytosis assay PCV-7 Heptavalent pneumococcal conjugate vaccine PE phycoerythrin PE-Cy5 PE-cyanin 5 PHA Phytohemagglutinin PI Phagocytosis index PPV valent pneumococcal polysaccharide vaccine RPMI Roswell Park Memorial Institute medium RTE Recent thymic emigrants SHM Somatic hypermutation SPAD Specific anti-polysaccharide antibody deficiency Tc Cytotoxic T TD T-cell dependent Th Helper-T TI T-cell independent TNF Tumour necrosis factor TREC T-cell-receptor excision circle TT Tetanus Toxoid 12 List of Abbreviations 167

10

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/43530 holds various files of this Leiden University dissertation. Author: Stijntjes, M. Title: Interactions of cognitive and physical ageing Issue Date:

Nadere informatie

Publications PUBLICATIONS

Publications PUBLICATIONS Publications 164 Publications PUBLICATIONS 1. Heemskerk B, Veltrop-Duits LA, van Vreeswijk T, ten Dam MM, Heidt S, Toes RE, van Tol MJ, Schilham MW. Extensive cross-reactivity of CD4 + adenovirus-specific

Nadere informatie

ABBREVRIATIONS. Antigen Induced Cell Death Antigen Presenting Cell. T cell receptor

ABBREVRIATIONS. Antigen Induced Cell Death Antigen Presenting Cell. T cell receptor ABBREVRIATIONS AICD APC BCR CCL-4 CCR7 CM cell cpbl CPM CTLA-4 (CD152) DC d.basalis d.parietalis EM cell FOXP3 HLA IDO IFN- IL ITAM ITIM KIR MHC mpbl NK cell RSA SI STBM TCR TGF- Tact Treg TNF- UCB Antigen

Nadere informatie

Immunizations in immunocompromised hosts:

Immunizations in immunocompromised hosts: 1 1 1 1 1 1 1 Immunizations in immunocompromised hosts: effects of immune modulating drugs and HIV on the humoral immune response Luc Ben Stefan Gelinck 1 1 1 1 1 1 1 Copyright L.B.S. Gelinck, Leidschendam,

Nadere informatie

Cover Page. Author: Heijden, Thomas van der Title: The interplay between lipids and the immune system in atherosclerosis Date:

Cover Page. Author: Heijden, Thomas van der Title: The interplay between lipids and the immune system in atherosclerosis Date: Cover Page The handle http://hdl.handle.net/1887/58107 holds various files of this Leiden University dissertation Author: Heijden, Thomas van der Title: The interplay between lipids and the immune system

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/45778 holds various files of this Leiden University dissertation Author: Korndewal, Marjolein Title: Consequences of congenital cytomegalovirus infection

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/23080 holds various files of this Leiden University dissertation. Author: Commandeur, Susanna Title: Facing the phases of Mycobacterium tuberculosis : hunting

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/51103 holds various files of this Leiden University dissertation Author: Goemans, A. Title: The development of children in foster care Issue Date: 2017-06-27

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/55514 holds various files of this Leiden University dissertation. Author: Maanen, E.M.T. van Title: Systems pharmacology of the amyloid cascade : unfolding

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/29345 holds various files of this Leiden University dissertation.

Cover Page. The handle http://hdl.handle.net/1887/29345 holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/29345 holds various files of this Leiden University dissertation. Author: Kusters, Maria Antonia Adriana (Maaike) Title: Adaptive immune system and vaccination

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/20183 holds various files of this Leiden University dissertation. Author: Rooden, Stephanie Maria van Title: Clinical patterns in Parkinson s disease Date:

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/28694 holds various files of this Leiden University dissertation. Author: Penning, Maria Elisabeth (Marlies) Title: On renal pathophysiology in preeclampsia

Nadere informatie

Cover Page. Author: Aa, Marloes van der Title: Diagnosis and treatment of obese children with insulin resistance Issue Date:

Cover Page. Author: Aa, Marloes van der Title: Diagnosis and treatment of obese children with insulin resistance Issue Date: Cover Page The handle http://hdl.handle.net/1887/44921 holds various files of this Leiden University dissertation Author: Aa, Marloes van der Title: Diagnosis and treatment of obese children with insulin

Nadere informatie

ASO: Toon Schiemsky Supervisor: Prof. Dr. X. Bossuyt Datum: 15 maart Optimalisatie van de pneumokokken polysacharide antistoffen test

ASO: Toon Schiemsky Supervisor: Prof. Dr. X. Bossuyt Datum: 15 maart Optimalisatie van de pneumokokken polysacharide antistoffen test ASO: Toon Schiemsky Supervisor: Prof. Dr. X. Bossuyt Datum: 15 maart 2016 Optimalisatie van de pneumokokken polysacharide antistoffen test Inleiding pneumokokken polysacharide antistoffen test Inleiding

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/24307 holds various files of this Leiden University dissertation Author: Broek, Colette van den Title: Optimisation of colorectal cancer treatment Issue

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/74052 holds various files of this Leiden University dissertation. Author: Winder, J.Y. Title: The UHDRS and UHDRS-FAP assessments in Huntington's disease

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/22989 holds various files of this Leiden University dissertation Author: Pouw, Lucinda Title: Emotion regulation in children with Autism Spectrum Disorder

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/18692 holds various files of this Leiden University dissertation. Author: Herbert-Fransen, Marieke Fernande Title: Targeting the tumor-draining area : local

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/33187 holds various files of this Leiden University dissertation

Cover Page. The handle http://hdl.handle.net/1887/33187 holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/33187 holds various files of this Leiden University dissertation Author: Hidding, Elske Title: Neurocognitive mechanisms and vulnerability to autism and

Nadere informatie

Citation for published version (APA): Ruizendaal, E. (2017). Malaria in pregnancy: In search of tools for improved prevention

Citation for published version (APA): Ruizendaal, E. (2017). Malaria in pregnancy: In search of tools for improved prevention UvA-DARE (Digital Academic Repository) Malaria in pregnancy Ruizendaal, E. Link to publication Citation for published version (APA): Ruizendaal, E. (2017). Malaria in pregnancy: In search of tools for

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/18704 holds various files of this Leiden University dissertation. Author: Borgdorff, Hendrik Anne (Henk) Title: The conflict of the faculties : perspectives

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/28692 holds various files of this Leiden University dissertation Author: Slingerland, Marije Title: Exploring novel formulations and new classes of anticancer

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/22866 holds various files of this Leiden University dissertation. Author: Voorthuis, Alexandra Title: Future parents : childhood experiences, oxytocin and

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/39413 holds various files of this Leiden University dissertation Author: Reedeker, Nanda Title: Neuropsychiatric phenomena in Huntington s disease Issue

Nadere informatie

Bacterial meningitis: epidemiology, herd protection, clinical characteristics, and risk assessment Bijlsma, M.W.

Bacterial meningitis: epidemiology, herd protection, clinical characteristics, and risk assessment Bijlsma, M.W. UvA-DARE (Digital Academic Repository) Bacterial meningitis: epidemiology, herd protection, clinical characteristics, and risk assessment Bijlsma, M.W. Link to publication Citation for published version

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/47927 holds various files of this Leiden University dissertation Author: Kerkman, Priscilla F. Title: Identification and characterization of anti-citrullinated

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/43352 holds various files of this Leiden University dissertation. Author: Velden, D. van der Title: Mast cell-mediated immune modulation in experimental

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/22212 holds various files of this Leiden University dissertation. Author: Wilde, Adriaan Hugo de Title: Host factors in nidovirus replication Issue Date:

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/37815 holds various files of this Leiden University dissertation. Author: Kleibeuker, Sietske Willemijn Title: 'What Box?': behavioral, neuro-imaging, and

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/23080 holds various files of this Leiden University dissertation. Author: Commandeur, Susanna Title: Facing the phases of Mycobacterium tuberculosis : hunting

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/31437 holds various files of this Leiden University dissertation Author: Rijssel, Erwin Roelof van Title: Stereoelectronic and conformational effects in

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/19332 holds various files of this Leiden University dissertation. Author: Duinen, Nicolette van Title: Hereditary paragangliomas : clinical studies Issue

Nadere informatie

Effectiviteit van BMR-vaccinatie gegeven voor de leeftijd van 14 maanden op korte en lange termijn: een afweging

Effectiviteit van BMR-vaccinatie gegeven voor de leeftijd van 14 maanden op korte en lange termijn: een afweging Effectiviteit van BMR-vaccinatie gegeven voor de leeftijd van 14 maanden op korte en lange termijn: een afweging Voor kinderen met een hoog risico op blootstelling aan mazelen weegt het positieve aspect

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/23005 holds various files of this Leiden University dissertation Author: Stoutjesdijk, Regina Title: Children with emotional and behavioral disorders in

Nadere informatie

Citation for published version (APA): Hartman, H. T. (2017). The burden of myocardial infarction [Groningen]: Rijksuniversiteit Groningen

Citation for published version (APA): Hartman, H. T. (2017). The burden of myocardial infarction [Groningen]: Rijksuniversiteit Groningen University of Groningen The burden of myocardial infarction Hartman, Hermina IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/32035 holds various files of this Leiden University dissertation Author: Kleijwegt, Fleur Title: Immune regulation in type 1 diabetes : towards a tissue

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/28971 holds various files of this Leiden University dissertation Author: Rosalia, Rodney Alexander Title: Particulate based vaccines for cancer immunotherapy

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net// holds various files of this Leiden University dissertation. Author: Verbiest, Marjolein Elisabeth Anna Title: The implementation of smoking cessation care

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/22746 holds various files of this Leiden University dissertation. Author: Jong, Ana Rae de Title: Development of synthetic procedures towards immunostimulating

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/40905 holds various files of this Leiden University dissertation. Author: Ateba Ngoa, U. Title: The effect of parasitic co-infections on immune responses

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/37233 holds various files of this Leiden University dissertation Author: Tummers, Bart Title: Human papillomavirus targets crossroads in immune signaling

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/24405 holds various files of this Leiden University dissertation. Author: Wevers- de Boer, Kirsten Vera Caroline Title: Improving disease outcomes in early

Nadere informatie

Curriculum Vitae 207

Curriculum Vitae 207 Curriculum Vitae 207 208 Curriculum Vitae Curriculum Vitae Joery Goede 8 augustus 1979, Amsterdam 1992-1998 Voortgezet Wetenschappelijk Onderwijs Stedelijk Gymnasium Haarlem 1998-2005 Studie Geneeskunde

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/66118 holds various files of this Leiden University dissertation. Author: Duijn, S. van Title: MRI and histologic studies on early markers of Alzheimer's

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/45043 holds various files of this Leiden University dissertation. Author: Plak, R.D. Title: What works for whom? Differential genetic effects of early literacy

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/38737 holds various files of this Leiden University dissertation Author: Goeij, Bart E.C.G. de Title: Antibody-drug conjugates in cancer Issue Date: 2016-04-13

Nadere informatie

Meningokokken ACWY-vaccinatie Richtlijn 1. Achtergrond

Meningokokken ACWY-vaccinatie Richtlijn 1. Achtergrond Meningokokken ACWY-vaccinatie Richtlijn Sinds 2010 is een conjugaatvaccin tegen meningokokken ACWY geregistreerd voor gebruik in Nederland. Het doel van vaccinatie met dit vaccin is om iemand te beschermen

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/31592 holds various files of this Leiden University dissertation. Author: Dierselhuis, Miranda Pauline Title: Minor histocompatibility antigen specific

Nadere informatie

The transferrin receptor at the blood-brain barrier: Exploring the possibilities for brain drug delivery

The transferrin receptor at the blood-brain barrier: Exploring the possibilities for brain drug delivery The transferrin receptor at the blood-brain barrier: Exploring the possibilities for brain drug delivery The transferrin receptor at the blood-brain barrier: Exploring the possibilities for brain drug

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/22618 holds various files of this Leiden University dissertation Author: Schans, Martin van der Title: Blowup in the complex Ginzburg-Landau equation Issue

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/18641 holds various files of this Leiden University dissertation.

Cover Page. The handle http://hdl.handle.net/1887/18641 holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/18641 holds various files of this Leiden University dissertation. Author: Vries, Jutte Jacoba Catharina de Title: Congenital cytomegalovirus infection :

Nadere informatie

CHIMERISM IN HEALTH, TRANSPLANTATION AND AUTOIMMUNITY

CHIMERISM IN HEALTH, TRANSPLANTATION AND AUTOIMMUNITY CHIMERISM IN HEALTH, TRANSPLANTATION AND AUTOIMMUNITY CHIMERISM IN HEALTH, TRANSPLANTATION AND AUTOIMMUNITY Thesis, University of Leiden, The Netherlands The studies described in this thesis were performed

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/26937 holds various files of this Leiden University dissertation Author: Klein-Wieringa, Inge Ragna Title: Adipose tissue inflammation : implications for

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/20154 holds various files of this Leiden University dissertation. Author: Joosen, Katharina Jacomina Title: Harsh discipline in toddlerhood. A longitudinal

Nadere informatie

Vaccinaties na allogene SCT Van feiten en fictie. DHC 2017 Ellen Meijer Vumc

Vaccinaties na allogene SCT Van feiten en fictie. DHC 2017 Ellen Meijer Vumc Vaccinaties na allogene SCT Van feiten en fictie DHC 2017 Ellen Meijer Vumc Belangenverklaring In overeenstemming met de regels van de Inspectie van de Gezondheidszorg (IGZ) Naam: Organisatie: Meijer Vumc

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/36475 holds various files of this Leiden University dissertation. Author: Windhorst, Dina Aafje (Dafna) Title: Differential susceptibility to parenting

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/19123 holds various files of this Leiden University dissertation. Author: Hoohenkerk, Gerard Joannes Franciscus Title: Surgical correction of atrioventricular

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/44387 holds various files of this Leiden University dissertation. Author: Staveren, M.C. van Title: DPD screening to prevent toxicity in fluoropyrimidine

Nadere informatie

Citation for published version (APA): Holwerda, A. (2013). Work outcome in young adults with disabilities Groningen: s.n.

Citation for published version (APA): Holwerda, A. (2013). Work outcome in young adults with disabilities Groningen: s.n. University of Groningen Work outcome in young adults with disabilities Holwerda, Anja IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/19067 holds various files of this Leiden University dissertation. Author: Meevissen, Moniek Hubertina Joanna Title: Schistosoma mansoni egg glycoproteins

Nadere informatie

Anxiety, fainting and gagging in dentistry: Separate or overlapping constructs? van Houtem, C.M.H.H.

Anxiety, fainting and gagging in dentistry: Separate or overlapping constructs? van Houtem, C.M.H.H. UvA-DARE (Digital Academic Repository) Anxiety, fainting and gagging in dentistry: Separate or overlapping constructs? van Houtem, C.M.H.H. Link to publication Citation for published version (APA): van

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/20734 holds various files of this Leiden University dissertation. Author: Jong, Romi de Title: Student teachers' practical knowledge, discipline strategies,

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/33229 holds various files of this Leiden University dissertation. Author: Rooden, Sanneke van Title: MR imaging in cerebral amyloidoses : entering a new

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/37530 holds various files of this Leiden University dissertation. Author: Nielen, Thijs Martinus Johannes Title: Aliteracy : causes and solutions Issue

Nadere informatie

Balancing effector lymphocyte formation via CD27-CD70 interactions Arens, R.

Balancing effector lymphocyte formation via CD27-CD70 interactions Arens, R. UvA-DARE (Digital Academic Repository) Balancing effector lymphocyte formation via CD27-CD70 interactions Arens, R. Link to publication Citation for published version (APA): Arens, R. (2003). Balancing

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/29019 holds various files of this Leiden University dissertation. Author: Ariotti, Silvia Title: Function and behavior of CD8+ T cells in the skin Issue

Nadere informatie

Cover Page. Author: Wezel, Anouk Title: Innate immune modulation in atherosclerosis and vascular remodelling Issue Date:

Cover Page. Author: Wezel, Anouk Title: Innate immune modulation in atherosclerosis and vascular remodelling Issue Date: Cover Page The handle http://hdl.handle.net/1887/29988 holds various files of this Leiden University dissertation Author: Wezel, Anouk Title: Innate immune modulation in atherosclerosis and vascular remodelling

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/37023 holds various files of this Leiden University dissertation.

Cover Page. The handle http://hdl.handle.net/1887/37023 holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/37023 holds various files of this Leiden University dissertation. Author: Wong, Chung Sing Title: The synthesis of mannose-derived bioconjugates and enzyme

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/45885 holds various files of this Leiden University dissertation. Author: Kersten, K. Title: Pulling the strings on anti-cancer immunity Issue Date: 2017-02-07

Nadere informatie

Hepatitis A. Transmissiedag Infectieziekten 14 september 2010

Hepatitis A. Transmissiedag Infectieziekten 14 september 2010 Hepatitis A Transmissiedag Infectieziekten 14 september 2010 Pierre Van Damme, MD, PhD Centrum voor de Evaluatie van Vaccinaties Vaccin & Infectieziekten Instituut Referentiecentrum WGO, Universiteit Antwerpen

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/36998 holds various files of this Leiden University dissertation. Author: Dunnen, Angela den Title: Surface-structure dependencies in catalytic reactions

Nadere informatie

List of publications. List of publications

List of publications. List of publications List of publications List of publications E. Sterrenburg, R. Turk, J.M. Boer, G.J.B. van Ommen and J.T. den Dunnen. A common reference for cdna microarray hybridizations. Nucleic Acids Res. 2002 Nov 1;30(21):e116

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/18701 holds various files of this Leiden University dissertation. Author: Gent, Tiejo van Title: Mental health problems in deaf and severely hard of hearing

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/48860 holds various files of this Leiden University dissertation Author: Rotman, M. Title: Crossing barriers, delivery of llama antibody fragments into

Nadere informatie

University of Groningen. Pieces of the Puzzle Vissia, Eline Margreta

University of Groningen. Pieces of the Puzzle Vissia, Eline Margreta University of Groningen Pieces of the Puzzle Vissia, Eline Margreta IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document

Nadere informatie

Basisprincipes tumorimmunologie

Basisprincipes tumorimmunologie Basisprincipes tumorimmunologie Joost Lesterhuis Afd. Medische Oncologie en Tumor Immunologie Nijmegen Centre for Molecular Life Sciences Het afweersysteem beschermt tegen kanker Risico op kanker neemt

Nadere informatie

LCI-richtlijn Kinkhoest

LCI-richtlijn Kinkhoest LCI-richtlijn Kinkhoest Diagnostiek (met medewerking van de NVMM) Microbiologische diagnostiek Directe diagnostiek Voor detectie van infectie met B.pertussis is PCR van nasofaryngeaal materiaal aanzienlijk

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/33676 holds various files of this Leiden University dissertation. Author: Huis-Tanja, Lieke Henriëtte van Title: Pharmacogenetics of capecitabine and oxaliplatin

Nadere informatie

Praktijkgericht onderwerp 3

Praktijkgericht onderwerp 3 Praktijkgericht onderwerp 3 Antistof therapie: gevolgen voor flow cytometrische diagnostiek. Andries Bloem Hoofd Diagnostiek Laboratorium voor Translationele Immunologie November 2017 The Netherlands Antistof

Nadere informatie

Helminth infections induce immunomodulation: consequences and mechanisms

Helminth infections induce immunomodulation: consequences and mechanisms Helminth infections induce immunomodulation: consequences and mechanisms Thesis by: Elly van Riet Promotores: Prof. dr. M. Yazdanbakhsh Prof. dr. A.G.M. Tielens Copromotor: Dr. F.C. Hartgers Leiden University

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/19745 holds various files of this Leiden University dissertation.

Cover Page. The handle http://hdl.handle.net/1887/19745 holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/19745 holds various files of this Leiden University dissertation. Author: Faaij, Claudia Margaretha Johanna Maria Title: Cellular trafficking in haematological

Nadere informatie

New applications of. UVA-1cold light therapy

New applications of. UVA-1cold light therapy New applications of UVA-1cold light therapy Polderman, Marloes Christina Abichael New applications ofuva-1cold light therapy/marloes C.A.Polderman PhD Thesis, Leiden University-W ith references -W ith

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle  holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/43439 holds various files of this Leiden University dissertation Author: Drozdovskaya, Maria Title: Inextricable ties between chemical complexity and dynamics

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/25886 holds various files of this Leiden University dissertation.

Cover Page. The handle http://hdl.handle.net/1887/25886 holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/25886 holds various files of this Leiden University dissertation. Author: Ketelaar, Lizet Title: Beyond hearing : social-emotional outcomes following cochlear

Nadere informatie

Kristien Wouters Tom Platteau Instituut voor Tropische Geneeskunde Antwerpen kwouters@itg.be tplatteau@itg.be

Kristien Wouters Tom Platteau Instituut voor Tropische Geneeskunde Antwerpen kwouters@itg.be tplatteau@itg.be HIV testen en teststrategieën Kristien Wouters Tom Platteau Instituut voor Tropische Geneeskunde Antwerpen kwouters@itg.be tplatteau@itg.be Structuur van de les Epidemiologie in België: www.wiv-isp.be;

Nadere informatie

University of Groningen. On physical functioning after pediatric burns Disseldorp, Laurien Maria

University of Groningen. On physical functioning after pediatric burns Disseldorp, Laurien Maria University of Groningen On physical functioning after pediatric burns Disseldorp, Laurien Maria IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/19074 holds various files of this Leiden University dissertation.

Cover Page. The handle http://hdl.handle.net/1887/19074 holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/19074 holds various files of this Leiden University dissertation. Author: Suwannalai, Parawee Title: ACPA response in evolution of rheumatoid arthritis

Nadere informatie

Acknowledgement. Acknowledgement

Acknowledgement. Acknowledgement Acknowledgement Acknowledgement This study is part of TREND (Trauma RElated Neuronal Dysfunction), a Dutch Consortium that integrates research on epidemiology, assessment technology, pharmacotherapeutics,

Nadere informatie

CAT Critically Appraised Topic. Optimalisatie van de pneumokokken polysacharide antistoffen test

CAT Critically Appraised Topic. Optimalisatie van de pneumokokken polysacharide antistoffen test CAT Critically Appraised Topic Optimalisatie van de pneumokokken polysacharide antistoffen test Author: Toon Schiemsky Supervisor: prof. dr. Xavier Bossuyt Date: 15-03-2016 CLINICAL BOTTOM LINE In de diagnostiek

Nadere informatie

University of Groningen. Structured diabetes care in general practice Fokkens, Sudara Andrea

University of Groningen. Structured diabetes care in general practice Fokkens, Sudara Andrea University of Groningen Structured diabetes care in general practice Fokkens, Sudara Andrea IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/45220 holds various files of this Leiden University dissertation Author: Vries, Bart de Title: Burgemeesters in crisistijd : de invloed van context en persoonlijkheid

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/33222 holds various files of this Leiden University dissertation

Cover Page. The handle http://hdl.handle.net/1887/33222 holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/33222 holds various files of this Leiden University dissertation Author: Braak, Bas ter Title: Carcinogenicity of insulin analogues Issue Date: 2015-06-18

Nadere informatie

Curriculum vitae and List of publications

Curriculum vitae and List of publications Curriculum vitae and List of publications Curriculum vitae Bert Arets werd geboren op 4 mei 1965 te Beek (L). In 1983 werd het VWO diploma behaald aan de Serviam Scholengemeenschap te Sittard. Hetzelfde

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/47927 holds various files of this Leiden University dissertation Author: Kerkman, Priscilla F. Title: Identification and characterization of anti-citrullinated

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle   holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/45545 holds various files of this Leiden University dissertation. Author: Beenakker, K.G.M. Title: The role of inflammation in muscle aging Issue Date:

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation.

Cover Page. The handle  holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/36026 holds various files of this Leiden University dissertation. Author: Hovens, Jacqueline Gerarda Francisca Maria Title: Emotional scars : impact of

Nadere informatie

Cover Page. The handle http://hdl.handle.net/1887/35006 holds various files of this Leiden University dissertation.

Cover Page. The handle http://hdl.handle.net/1887/35006 holds various files of this Leiden University dissertation. Cover Page The handle http://hdl.handle.net/1887/35006 holds various files of this Leiden University dissertation. Author: Pasma, Jantsje Henrieke Title: Impaired standing balance : unraveling the underlying

Nadere informatie

Figure 1 Shares of Students in Basic, Middle, and Academic Track of Secondary School Academic Track Middle Track Basic Track 29 Figure 2 Number of Years Spent in School by Basic Track Students 9.5 Length

Nadere informatie

Cover Page. The handle holds various files of this Leiden University dissertation

Cover Page. The handle   holds various files of this Leiden University dissertation Cover Page The handle http://hdl.handle.net/1887/47238 holds various files of this Leiden University dissertation Author: Philipsen, Cheryl Title: Unraveling the auxin mechanism in 2,4-D induced somatic

Nadere informatie

Sjögren s syndrome: new animal models and salivary gland therapies

Sjögren s syndrome: new animal models and salivary gland therapies UvA-DARE (Digital Academic Repository) Sjögren s syndrome: new animal models and salivary gland therapies Vosters, J.L.G. Link to publication Citation for published version (APA): Vosters, J. L. G. (2011).

Nadere informatie