UvA-DARE (Digital Academic Repository) Hereditary & familial colorectal cancer Kallenberg, F.G.J. Link to publication Citation for published version (APA): Kallenberg, F. G. J. (2017). Hereditary & familial colorectal cancer: Identification, characteristics, surveillance General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. UvA-DARE is a service provided by the library of the University of Amsterdam (http://dare.uva.nl) Download date: 18 Sep 2017
HEREDITARY & FAMILIAL COLORECTAL CANCER Identification, Characteristics, Surveillance Frank Kallenberg
ISBN: 978-94-6182-809-5 Cover design: Julian Schönfeld, www.julianschonfeld.nl Layout and printing: Off Page, Amsterdam, www.offpage.nl The printing of this thesis was financially supported by: Academic Medical Center Amsterdam, Nederlandse Vereniging voor Gastroenterologie, ChipSoft, Castor EDC, Pfizer bv, Erbe Nederland B.V., Tramedico B.V., Norgine B.V., US Endoscopy The study reported in Chapter 3 was funded by the Dutch Digestive Foundation Copyright 2017 F.G.J. Kallenberg. All rights reserved. No part of this thesis may be reproduced, stored or transmitted in any form or by any means without permission of the author or publishers of the included scientific papers
HEREDITARY & FAMILIAL COLORECTAL CANCER Identification, Characteristics, Surveillance ACADEMISCH PROEFSCHRIFT ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam op gezag van de Rector Magnificus prof. dr. ir. K.I.J. Maex ten overstaan van een door het College voor Promoties ingestelde commissie, in het openbaar te verdedigen in de Aula der Universiteit op vrijdag 8 september 2017, te 11.00 uur door Frank Gijsbert Jan Kallenberg geboren te Groningen
PROMOTIECOMMISSIE Promotores Prof. dr. E. Dekker AMC-UvA Prof. dr. P.M.M. Bossuyt AMC-UvA Copromotor Dr. C.M. Aalfs AMC-UvA Overige leden Prof. dr. E.J. Meijers-Heijboer AMC-UvA Prof. dr. W.A. Bemelman AMC-UvA Prof. dr. E.M.H. Mathus-Vliegen AMC-UvA Dr. F.M. Nagengast Radboud Universiteit Nijmegen Prof. dr. R.H. Sijmons Rijksuniversiteit Groningen Dr. R. Jover Martínez Universidad de Alicante Faculteit der Geneeskunde
TABLE OF CONTENTS Chapter 1 PART I Chapter 2 Chapter 3 Chapter 4 PART II Chapter 5 Chapter 6 Chapter 7 Chapter 8 Chapter 9 Chapter 10 Appendix General introduction Identification of familial colorectal cancer and hereditary colorectal cancer syndromes Validation of an online questionnaire for identifying people at risk of familial and hereditary colorectal cancer Familial Cancer 2015 Evaluation of an online family history tool for identifying hereditary and familial colorectal cancer Submitted Adding family history to faecal immunochemical testing increases the detection of advanced neoplasia in a colorectal cancer screening programme Alimentary Pharmacology & Therapeutics 2016 Etiology, characteristics and surveillance in adenomatous polyposis syndromes A case series of intestinal adenomatous polyposis of unidentified etiology; a late effect of irradiation? BMC Cancer 2016 Duodenal adenomas in patients with multiple colorectal adenomas without germline APC or MUTYH mutations Diseases of the Colon & Rectum 2017 Frequency and features of duodenal adenomas in patients with MUTYHassociated polyposis Clinical Gastroenterology and Hepatology 2016 Cap-assisted forward-viewing endoscopy to visualize the ampulla of Vater and the duodenum in patients with familial adenomatous polyposis Endoscopy 2017 Adrenal lesions in patients with (attenuated) familial adenomatous polyposis and MUTYH-associated polyposis Diseases of the Colon & Rectum 2017 Thesis summary and future perspectives Nederlandse samenvatting Contributing authors List of publications PhD portfolio Acknowledgements/Dankwoord About the author 7 17 19 39 59 75 77 89 107 123 133 151 169 175 177 179 183 187