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1 Cover Page The handle holds various files of this Leiden University dissertation. Author: Hommes, M. Title: The injured liver : management and hepatic injuries in the traumapatient Issue Date:

2 List of Publications List of Publications Nicol AJ, Navsaria PH, Beningfield S, Hommes M, Kahn D. Screening for occult penetrating cardiac injuries. Ann Surg Mar;261(3): Nicol AJ, Navsaria P, Hommes M, Ball C, Edu S, Kahn D. Sternotomy or Drainage for a Hemopericardium After Penetrating Trauma: A Safe Procedure? Ann Surg Feb 2 Epubhead of Print. Hommes M, Nicol AJ, Navsaria PH, Reinders Folmer E, Edu S, Krige JE. Management of biliary complications in 412 patients with liver injuries. J Trauma Acute Care Surg Sep;77(3): Hommes M, Navsaria PH, Schipper IB, Krige JE, Kahn D, Nicol AJ. Management of blunt liver trauma in 134 severely injured patients. Injury.2015 May;46(5): Nicol AJ, Navsaria PH, Hommes M, Edu S, Kahn D. Management of a pneumopericardium due to penetrating trauma. Injury Sep;45(9): Hommes M, Nicol AJ, van der Stok J, Kodde I, Navsaria PH. Subxiphoid pericardial window to exclude occult cardiac injury after penetrating thoracoabdominal trauma. Br J Surg Oct;100(11): Nicol AJ, Navsaria PH, Hommes M, Ball CG, Edu S, Kahn D. Sternotomy or drainage for a hemopericardium after penetrating trauma: a randomized controlled trial. Ann Surg Mar;259(3): Hommes M, Kazemier G, Schep NWL, Kuipers EJ, Schipper IB. Management of biliary complications following damage control surgery for liver trauma. Eur J Tr Emerg Surg. 2013, 39 (5) Hommes M, Kazemier G, van Dijk LC, Kuipers EJ, van Ijsseldijk A, Vogels LM, Schipper IB. Complex liver trauma with bilhemia treated with perihepatic packing and endovascular stent in the vena cava. J Trauma Aug;67(2):E51-3. Hommes M, Waes OJF van, Meynaar IA, Koning J. Continous measurement of bladder pressure is equal to discontinous measurement of the bladder pressure via the Krohn s method. Abstracts of the World Society of Abdominal Compartment Syndrome meeting, June , Trinity College, Dublin, Ireland.Acta Clin Belg 2009;64(3):

3 Hommes M, Goslings JC, van Gulik TM. Blunt abdominal trauma leading to traumatic transection of the liver without massive hemorrhage. J Trauma Aug;65(2):E21-3. Nicol AJ, Hommes M, Primrose R, Navsaria PH, Krige JE. Packing for control of hemorrhage in major liver trauma. World J Surg Mar;31(3): Hommes M, Hoskam JA. A man with a tongue disorder. Black hairy tongue].ned Tijdschr Geneeskd May 15;148(20):984. Dutch. Van Rijen MM, Metselaar HJ, Hommes M, Ijzermans JN, Tilanus HW, Kwekkeboom J. Mycophenolic acid is a potent inhibitor of the expression of tumour necrosis factorand tumour necrosis factor-receptor superfamily costimulatory molecules. Immunology May;109(1):

4 Dankwoord/Acknowledgements Dankwoord/Acknowledgements Dit proefschrift zou niet tot stand zijn gekomen zonder de bijdragen van vele personen. Daarvoor wil ik een ieder van harte dank zeggen, maar een aantal wil ik met name noemen. Prof.dr. I.B. Schipper, beste Inger, heel veel dank voor je inspiratie, adviezen en steun om dit deels in het buitenland uitgevoerd project te mogen uitwerken tot dit proefschrift. Professor Andrew Nicol, professor Pradeep Navsaria, professor Jake Krige, professor Del Kahn and Sorin Edu, thanks for offering the opportunity to do my research in the Groote Schuur Hospital. Especially Andrew, Pradeep and professor Krige thanks for your critical input and editorial advice when writing this PhD-thesis. It was a pleasure having the opportunity learning from you and working with you together. De leden van de promotiecommissie, prof. dr. C. Goslings, prof.dr. R.S. Breederveld, prof dr. B. van Hoek en prof. dr. H.W. Tilanus, wil ik van harte danken voor de moeite die zij hebben genomen bij het beoordelen van dit proefschrift. Prof.dr. G. Kazemier, prof.dr. R.J.M. Klautz en prof.dr. L.P.H.J. Aarts, wil ik van harte danken voor hun bereidheid zitting te willen nemen in de oppositiecommissie ter verdediging van dit proefschrift. Dr. Pieta Krijnen en Eline reinders Folmer, wil ik in het bijzonder danken voor hun hulp bij de analyse van de data en statistische ondersteuning in het algemeen. De studenten van het Erasmus Medisch Centrum,die als stagiaires betrokken waren bij het onderzoeksproject wil ik danken voor hun hulp bij het verzamelen van de data in Kaapstad. I want to thank Miriam, the secretary of the trauma unit of the Groote Schuur Ziekenhuis in Cape Town, for her administrative support of my research during my stay in South Africa. Graag wil ik ook een woord van dank richten tot prof.dr.p.a.m. Vierhout en Dr. H.F.Veen, die mij door de jaren heen hebben gemotiveerd door te gaan met mijn onderzoek en dit proefschrift af te ronden. 187

5 Aleida Hommes- de Vos van Steenwijk en Thomas Kölbl wil ik danken voor hun suggesties voor de laatste tekstuele aanpassingen en verbeteringen van het manuscript. Thanks a lot for your effort. Tenslotte past een bijzonder woord van dank aan Pieter Jan Bruynzeel, Philippe van Woerkom, Jurre Mulder, Thijs Dirkzwager, Vincent Vierhout, Marlies van Amerongen, Willem van der Vorm, Eric en Pia van der Vorm en mijn broer Tymon. Hun vriendschap en het door hen in mij gestelde vertrouwen zijn van uitzonderlijke betekenis geweest voor het voltooien van dit proefschrift. 188

6 Curriculum Vitae Curriculum Vitae Martijn Hommes is op 29 juni 1976 geboren in Groningen en behaalde het diploma VWO bij het Jacobus College in Enschede. Hij heeft zijn studie Geneeskunde gevolgd aan het Erasmus Universitair Medisch Centrum in Rotterdam. Gedurende een co-schap in het Groote Schuur Hospitaal in Kaapstad werd zijn belangstelling gewekt voor het onderzoek naar de behandeling van lever trauma s, onderwerp van dit proefschrift. In 2005 heeft Martijn de opleiding chirurgie aangevangen bij het Erasmus Universitair Medisch Centrum, Groote Schuur Hospitaal en Reinier de Graaf Groep (opleiders: prof. dr. J.N.M. Ijzermans (EMC), prof.dr.l.p.s. Stassen (RdGG) en dr. M. van der Elst (RdGG)). Martijn is sinds 2011 geregisteerd chirurg bij de Koninklijke Nederlandse Maatschappij ter bevordering der Geneeskunde en Nederlandse Vereniging van Heelkunde. In 2011, na afronding van zijn chirurgische opleiding, heeft hij een verdiepingstage Intensive Care Geneeskunde gevolgd bij het VU medisch centrum (prof.dr. A.R.J. Girbes). Daarna heeft hij een fellowship algemene trauma chirurgie vervuld bij de trauma unit van het Groote Schuur Hospitaal (Andrew Nicol en Pradeep Navsaria) en was geregistreerd bij de Health Profession Council of South Africa. Tegelijkertijd heeft hij daar de data verzameld die ten grondslag liggen aan dit proefschrift. Na afronding van het fellow- ship in het Groote Schuur Hospitaal is Martijn vanaf 2014 werkzaam als chirurg in Zwitserland en geregistreerd bij bij de Nederlandse Verening van Traumatologie. 189

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