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1 Cover Page The handle holds various files of this Leiden University dissertation. Author: Molendijk, Ilse Title: Mesenchymal stromal cell therapy for Crohn's disease : from perianal fistulizing disease to experimental colitis Issue Date:
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3 CHAPTER 11 LIST OF PUBLICATIONS CURRICULUM VITAE DANKWOORD LIST OF ABBREVIATIONS
4 CHAPTER 11 LIST OF PUBLICATIONS Molendijk I, Bonsing BA, Roelofs H et al. Allogeneic bone marrow-derived mesenchymal stromal cells promote healing of refractory perianal fistulas in patients with Crohn s disease. Gastroenterology. 2015;149: Voorneveld PW, Kodach LL,, Molendijk I et al. The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC. British Journal of Cancer. 2015;112: Molendijk I, Nuij VJAA, van der Meulen-de Jong AE, van der Woude CJ. Disappointing durable remission rates in complex Crohn s disease fistula. Inflammatory Bowel Diseases. 2014;20: Molendijk I, Peeters KCMJ, Baeten CIM et al. Improving the outcome of fistulising Crohn s disease. Best Practice & Research: Clinical Gastroenterology. 2014;28: Molendijk I. Literature review in ECCO News Summer Molendijk I, Hommes DW, Duijvestein M. Mesenchymal stromal cell therapy in Crohn s disease. In: Mesenchymal stem cell therapy. 2013; Springer text book. Molendijk I, Duijvestein M, van der Meulen-de Jong AE et al. Immunomodulatory effects of mesenchymal stromal cells in Crohn s disease. J Allergy (Cairo). 2012;2012: Molendijk I, Duijvestein M. Report from the 7th European Crohn s and Colitis Organization Congress. IBD Monitor. 2012;12: Duijvestein M, Wildenberg ME,, Molendijk I et al. Pretreatment with interferon-ɣ enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis. Stem Cells. 2011;29: Duijvestein M, Molendijk I, Roelofs H et al. Mesenchymal stromal cell function is not affected by drugs used in the treatment of inflammatory bowel disease. Cytotherapy. 2011;13:
5 11 CURRICULUM VITAE CURRICULUM VITAE Ilse Molendijk was born on November 15 th 1985, in Gouda, The Netherlands. After completing her secondary education at the Coornhert Gymnasium in Gouda she started her medical study in September 2003 at the Leiden University. For her Gynecology and Obstetrics internship in her fifth year she went to the Diakonessenhuis in Paramaribo, Suriname, for two months. During her internships Ilse s interest for Gastroenterology and Hepatology grew. Therefore, she completed her clinical rotations at the department of Gastroenterology and Hepatology in the Leiden University Medical Center. After spending a year of full-time chairmanship at her student society, she finished her medical study in February 2011 with a research internship entitled The clinical course of primary sclerosing cholangitis: predictors for liver transplantation and survival at the department of Gastroenterology and Hepatology in the Leiden University Medical Center under supervision of prof. dr. B. van Hoek. In March 2011 she started with her PhD traineeship at the same department under supervision of prof. dr. H.W. Verspaget and prof. dr. D.W. Hommes. The results are described in this thesis and presented at (inter)national conferences resulting in awards for poster of excellence (UEGW, 2013), best abstract of the session (ECCO, 2015) and best abstract of the entire conference (NvGE, 2015). Since March 2014 Ilse is vice-president of the Young Initiative on Crohn and Colitis (Y-ICC). In May 2015 Ilse started her residency Gastroenterology and Hepatology under supervision of dr. R.A. Veenendaal. Currently, Ilse is working at the Medisch Centrum Haaglanden in Leidschendam and Den Haag (supervisor: dr. A.H. Bootsma). 193
6 CHAPTER 11 DANKWOORD Allereerst gaat mijn dank uit naar mijn promotoren. Hein, dank voor jouw onvermoeibare inzet om al mijn onderzoeken, zowel basaal als klinisch, in goede banen te leiden. Niets was voor jou te veel! Daan, ondanks dat wij maar zeer kort op dezelfde locatie hebben gewerkt, wil ik je bedanken voor alle mogelijkheden die je mij hebt geboden. Jouw altijd positieve houding heeft veel bijgedragen aan het tot een succes maken van mijn promotie. Ook mijn co-promotor, Andrea, bedankt voor het vertrouwen en de vrijheid die jij mij hebt gegeven om onze klinische trial tot een geweldig einde te brengen. Al mijn collega s van de Maag-, Darm- en Leverziekten wil ik bedanken voor zowel hun wetenschappelijke als gezellige inbreng de afgelopen jaren. Izak, bedankt voor jou bijdrage aan de muisproeven die ik heb uitgevoerd. Eveline, Marij, Johan, Wim en Annie, waar was ik zonder jullie geweest op het lab? Bedankt voor al jullie hulp! Ook Lokke en Cindy (stafsecretariaat), Marthe en Nienke (verpleegkundig specialisten IBD), Sandra, Babs, Lida, Siepke en Pauline (trialbureau) en iedereen van het polisecretariaat en de scopieafdeling wil ik bedanken voor hun inzet om mijn studies te laten slagen. Danny, Claire, Simone, Annarein, Sanne, Marieke, Lennart, Madelon, Luuk, Philip, Rutger, Liudmilla, Kerem, Bert-Jan, Auke, Tony, Lianne, Marjolijn, Christine en Manon, bedankt voor jullie hulp en steun! Daarnaast wil ik Marloes, Saskia en Marieke bedanken die in het kader van hun studie een stage bij mij hebben gelopen en mij erg veel werk uit handen hebben genomen. Ik ben trots dat Marieke naar aanleiding van haar stage dit geweldige onderzoek voort zal zetten. Dit proefschrift was niet tot stand gekomen zonder een aantal geweldige samenwerkingen. Martin, Bert en Koen, bedankt voor jullie gedrevenheid in het tot een goed einde brengen van onze klinische trial. Zonder jullie radiologische en chirurgische expertise was deze studie nooit zo n succes geworden! Collega's van de afdeling Immunohematologie en Bloedtransfusie Jorge, Melissa, Vanessa, Helene, Jaap-Jan, Vincent, Frits en Wim, zowel de basale als klinische onderzoeken zijn door jullie inbreng naar een hoger niveau getild. Dank hiervoor! Veerle en Janneke van het Erasmus MC in Rotterdam, bedankt voor jullie gedrevenheid waardoor we samen in zo n korte tijd een prachtig stuk hebben kunnen schrijven. Ook de bijeenkomsten met mijn bestuursgenoten van de Y-ICC en de gezellige etentjes mijn PhD-vriendinnen Carolien, Saskia en Simone hebben bijgedragen aan nieuwe inzichten voor verschillende experimenten. 194
7 11 DANKWOORD Een aantal mensen wil ik graag apart bedanken. Eveline, bedankt voor de prachtige voorkant van dit proefschrift! Mijn paranimfen Danny en Claire. In de afgelopen jaren hebben we lief en leed gedeeld in ons hok. Bedankt voor jullie steun, gezelligheid en geniale ideeën! Als laatste wil ik mijn ouders, zusje Marlieke en vriend(inn)en bedanken voor alle steun en gezelligheid. Speciale dank aan Michiel. De afgelopen jaren heb jij alles omtrent mijn promotie meegemaakt en ben jij altijd mijn grote steun en toeverlaat geweest. 195
Cover Page. The handle holds various files of this Leiden University dissertation
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Cover Page The handle http://hdl.handle.net/1887/20223 holds various files of this Leiden University dissertation. Author: Spijker, Anne Titia Title: Cortisol exposure, cognition and clinical course of
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Cover Page The handle http://hdl.handle.net/1887/44921 holds various files of this Leiden University dissertation Author: Aa, Marloes van der Title: Diagnosis and treatment of obese children with insulin
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Cover Page The handle http://hdl.handle.net/1887/37530 holds various files of this Leiden University dissertation. Author: Nielen, Thijs Martinus Johannes Title: Aliteracy : causes and solutions Issue
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Cover Page The handle http://hdl.handle.net/1887/37815 holds various files of this Leiden University dissertation. Author: Kleibeuker, Sietske Willemijn Title: 'What Box?': behavioral, neuro-imaging, and
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Cover Page The handle http://hdl.handle.net/1887/24378 holds various files of this Leiden University dissertation. Author: Melief, Sara Marie Title: Immunomodulatory properties of human multipotent stromal
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Cover Page The handle http://hdl.handle.net/1887/74052 holds various files of this Leiden University dissertation. Author: Winder, J.Y. Title: The UHDRS and UHDRS-FAP assessments in Huntington's disease
Publications PUBLICATIONS
Publications 164 Publications PUBLICATIONS 1. Heemskerk B, Veltrop-Duits LA, van Vreeswijk T, ten Dam MM, Heidt S, Toes RE, van Tol MJ, Schilham MW. Extensive cross-reactivity of CD4 + adenovirus-specific
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Cover Page The handle http://hdl.handle.net/1887/23005 holds various files of this Leiden University dissertation Author: Stoutjesdijk, Regina Title: Children with emotional and behavioral disorders in
Antipsychotics, brain morphology and duration of untreated illness in schizophrenia
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Dankwoord De afgelopen jaren heb ik altijd erg uitgegeken naar dit moment, maar nu blijkt het schrijven van een dankwoord een beetje een anticlimax. Niet het einde van het proefschrift maakt me wat weemoedig,
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Cover Page. Author: Dikken, Johannes Leen Title: Gastric cancer : staging, treatment, and surgical quality assurance Issue Date: 2012-09-26
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Cover Page The handle http://hdl.handle.net/1887/20183 holds various files of this Leiden University dissertation. Author: Rooden, Stephanie Maria van Title: Clinical patterns in Parkinson s disease Date:
CURRICULUM VITAE AND PUBLICATIONS
CURRICULUM VITAE AND PUBLICATIONS 168 CURRICULUM VITAE AND PUBLICATIONS CURRICULUM VITAE Laura Vroling werd geboren op 2 maart 1980 te Hoorn. In 1997 behaalde ze haar HAVO diploma aan de RSG te Enkhuizen.
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University of Groningen Geriatric Traumatology Folbert, Engelina IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document
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Cover Page The handle http://hdl.handle.net/1887/51103 holds various files of this Leiden University dissertation Author: Goemans, A. Title: The development of children in foster care Issue Date: 2017-06-27
Cover Page. The handle holds various files of this Leiden University dissertation.
Cover Page The handle http://hdl.handle.net/1887/20154 holds various files of this Leiden University dissertation. Author: Joosen, Katharina Jacomina Title: Harsh discipline in toddlerhood. A longitudinal
Acknowledgements Publications Curriculum vitae
Acknowledgements Publications Curriculum vitae 153 ACKNOWLEDGEMENTS In de afgelopen jaren heb ik van veel mensen begrip, ondersteuning, en opbeurende woorden gehad, zonder hen was het promotietraject
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Cover Page The handle http://hdl.handle.net/1887/23854 holds various files of this Leiden University dissertation. Author: Marel, Sander van der Title: Gene and cell therapy based treatment strategies
Citation for published version (APA): Hartman, H. T. (2017). The burden of myocardial infarction [Groningen]: Rijksuniversiteit Groningen
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University of Groningen The burden of myocardial infarction Hartman, Hermina IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check
Citation for published version (APA): Benditte-Klepetko, H. C. (2014). Breast surgery: A problem of beauty or health?
UvA-DARE (Digital Academic Repository) Breast surgery: A problem of beauty or health? Benditte-Klepetko, H.C. Link to publication Citation for published version (APA): Benditte-Klepetko, H. C. (2014).
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Cover Page The handle http://hdl.handle.net/1887/38545 holds various files of this Leiden University dissertation. Author: Molendijk, Ilse Title: Mesenchymal stromal cell therapy for Crohn's disease :
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Cover Page The handle http://hdl.handle.net/1887/59469 holds various files of this Leiden University dissertation Author: Jong, Anja de Title: Immunometabolism in osteoarthritis Date: 2018-02-20 Chapter
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Cover Page The handle http://hdl.handle.net/1887/19932 holds various files of this Leiden University dissertation. Author: Wardenaar, Klaas Johan Title: Syndromes versus symptoms : towards validation of
Nawoord. In het bijzonder wil ik noemen:
Curriculum Vitae De schrijver van dit proefschrift werd geboren op 13 februari 1966 te Pijnacker. In 1984 behaalde hij het VWO ß diploma aan het Christelijk Lyceum Delft, te Delft. In datzelfde jaar begon
Lize, bedankt voor de mooie cover en het opmaken van dit proefschrift, ik vind het prachtig geworden!
Velen van jullie zullen misschien gedacht hebben dat het er niet meer van zou komen. Nu het toch eindelijk zo ver is, wil ik de mensen bedanken die op enige wijze hebben bijgedragen aan dit proefschrift.