Sphingolipids, ABC transporters and chemosensitivity in neuroblastoma Dijkhuis, Anne-Jan

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1 Sphingolipids, ABC transporters and chemosensitivity in neuroblastoma Dijkhuis, Anne-Jan IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2006 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Dijkhuis, A-J. (2006). Sphingolipids, ABC transporters and chemosensitivity in neuroblastoma Groningen: s.n. Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date:

2 DANKWOORD

3 Nu mijn proefschrift klaar is wordt het tijd om iedereen te bedanken die betrokken is geweest bij het tot stand komen ervan. Laat ik beginnen met mijn copromotores en promotor. Jan Willem, ik ben van mening dat ik het niet beter had kunnen treffen met jou als copromotor. Je behulpzaamheid, creativiteit, je enthousiasme voor onderzoek en het feit dat je me in moeilijke tijden heb gesteund heb ik altijd erg gewaardeerd. Verder denk ik met veel plezier terug aan alle besprekingen, discussies, de lol om confocalplaatjes ( beertje ) en de fietstochten in hartje winter. Heel erg bedankt! Hannie, jou wil ik bedanken voor je betrokkenheid bij het project en de wijze waarop je me wist te motiveren. Gezien mijn achtergrond als biochemicus was jouw medische invalshoek voor mij van grote waarde. Jij en Jan Willem vormen een goed begeleidingsteam. Willem, ik wil jou bedanken voor je positieve en professionele bijdrage aan het project, je geduld en je vertrouwen in een goede afloop. Ik realiseer me dat we elkaar de afgelopen jaren niet altijd genoeg hebben gezien en gesproken. Toch wist jij precies hoe de zaken ervoor stonden. Karin, als het gaat om de praktische kant van het onderzoek was ik nergens geweest zonder jou. Niet alleen heb jij me alles geleerd wat nodig is om onderzoek te kunnen doen naar sfingolipiden, maar je hebt me ook heel veel werk uit handen genomen. Ik ben je veel dank verschuldigd. Verder was je gewoon een zeer prettige collega om mee samen te werken. Trouwens, nog bedankt dat je me ooit eens hebt geleerd hoe je een MTT doet ;-) Dan de DNA expert in het sfingolipidengroepje en tevens mijn trouwste kamergenote: Ina. Ina, bijna zes jaar met jou op een kamer was zeker geen straf. Naast serieuze discussies hebben we samen ook veel kunnen lachen (bijvoorbeeld over FCS). Daarbij heb je voor mij ook het nodige praktisch werk verricht. Jenny, Dennis, Anneke en Anne-Marije, mijn proefschrift had er ongetwijfeld anders uitgezien zonder jullie bijdragen. John en Tiemen wil ik bedanken voor de praktische tips en nuttige discussies. Mijn kamergenoten door de jaren heen: Ina, Nicole, Joke, Dona, Delphine (I did it too!) and Olaf, thank you all very much for the interesting conversations, good advice and the nice time! Alle andere collega s van de Membraan Celbiologie, jullie wil ik bedanken voor de goede sfeer binnen en buiten de muren van het lab - bijvoorbeeld omdat jullie grappig waren, in het lab aanwezig waren, mee waren tijdens labdagen, retraites, borrels, etentjes of bioscoopbezoek, toevallig konden skaten of meededen met voet- of volleybaltoernooien en voor jullie steun, hulp, adviezen of opbouwende kritiek. Mijn collega s van de Kinderoncologie wil ik vooral bedanken voor hun kritische vragen en suggesties tijdens de werkbesprekingen. Bart-Jan en Susan, bedankt voor onder andere de discussies en hulp bij het 134

4 FACSen. Zonder jullie bijdrage hadden we misschien nog niet geweten hoe paclitaxel/pdmp de celoverleving verlaagt. Prof. Dr. H.N. Caron, Prof. Dr. H.H. Kampinga en Prof. Dr. F. Kuipers wil ik hartelijk danken voor het feit dat ze bereid waren mijn manuscript aandachtig en kritisch door te lezen. In tijd van nood leert men zijn vrienden kennen. Jullie hebben bevestigd wat ik al wist: dat ik mij gelukkig mag prijzen met echte vrienden. Ik wil jullie bedanken voor jullie steun in een zeer moeilijke tijd. Martijn, Rutger en Kars, ik stel voor dat ze de 3,7 miljard van de Zuiderzeelijn nu besteden aan het verplaatsen van Groningen naar de Veluwezoom. Rob en Fiona, fijn dat ik altijd welkom was als ik weer eens onverwachts langskwam en bedankt voor jullie interesse en vrolijkheid. Karin en Mark, Mahjong! Zo, nu wordt het tijd voor een Frank, bedankt voor een luisterend oor en de gezelligheid. Lieve pa en ma, ik heb grote bewondering voor jullie. Jullie staan altijd voor me klaar. Bedankt voor jullie onvoorwaardelijke steun. Leendert en Judith, bedankt voor alle herinneringen die we samen hebben opgehaald. Karin, jij hebt de afgelopen jaren meer voor mij betekend dan je wellicht zelf beseft. Bedankt dat je me begrijpt en altijd hebt gesteund. Anne-Jan 135

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